Seeds grant vision to your team.
Placing a seed in your spell's path after you have cast it gives you the best chance of having a seed in the proper spot.
Zyra is a great ambusher - look for opportunities to set a trap of seeds in brush, then lure enemies in.
Lissandra's abilities are shorter range than those of many mages. As a result, buying items that offer both ability power and defense, like Zhonya's Hourglass and Banshee's Veil, can be a great choice to help her both survive and deal damage.
Casting Glacial Path and then running in the opposite direction will leave your enemies uncertain which way you will actually go.
You can instantly use your ultimate on yourself by pressing the self cast key and the ultimate key at once (alt+R by default).
The Zyra Lissandra synergy stats shown here demonstrate the areas of her gameplay that do better (or worse) when paired with Lissandra, compared to her overall stats. Significant differences are areas of focus that highlight how her gameplay changes when paired with this other champion.
Overall, Zyra sees a very large drop in her KDA (ratio of kills and assists to deaths) when paired with Lissandra. His KDA worsened from NaN to NaN. This negative change shows that Lissandra helps Zyra perform worse in ranked League of Legends rounds. Yet, the small difference proves that this performance change is not very impactful.
When Zyra is an ally to Lissandra, she observes a little decrease in her complete damage dealt. This may demonstrate that Lissandra does not provide protection for her to dish out more damage or that her support also helps increase the match's duration. Similarly, when Zyra is played with Lissandra on the same team, he usually scores many fewer killing sprees than when she plays alone. This is contrasting evidence that she is worse when playing synergisticly with Lissandra.
Moreover, when Zyra plays with Lissandra on the same team, she often takes a little less damage than when she plays alone. Receiving not as much damage may mean that Lissandra does a decent job of covering Zyra in teamfights.
There is no one best champion pairing for Zyra that will always be her #1 synergy. Yet, overall, Lissandra is a below average ally for Zyra. By locking into the same team as Zyra, she decreases their win rate by -1.3% to 51.3%. This demonstrates that there is a bad synergy between Zyra and Lissandra that results in them performing worse together than without each other.
Lissandra has a lower difficulty than Zyra. That means you don't need to be very careful when arranging Lissandra teammates to go into battle on the same side as, as they will have to have a relatively low level of skill to do well with you.
Playing cooperatively, you should expect to see an overall large increase in your team’s ability to deal magical damage. When paired, these champs can deal quite a lot of AP type damage.
Although, by grouping Zyra and Lissandra together, you will not be giving your other allies much AD. Make sure to bring other champions on your team that offsets this relative disparity in this pairing's playstyle.
Regardless of the ability of your Lissandra ally, you need to focus on maximizing your income, staying alive by avoiding foolish fights, and taking down objectives. If you do this, you will do well anyway.
If you would like to truly master Zyra in order to work well with Lissandra during both the lane and mid / late game phases of League of Legends rounds, you should continue reading to master some more tricks and insights into this champion pairing. If you use the build and suggestions shown here, you will increase your win rate by a lot.
The ideal items to have in your Zyra and Lissandra synergy build include Zhonya's Hourglass, Zaz'Zak's Realmspike, and Liandry's Torment. When Zyra bought at least these three pieces in her build, she performed significantly better as an ally of Lissandra than with most other commonly used item sets. In fact, Zyra boasted an average winrate of 51.3% when playing alongside Lissandra with these items in her kit.
To have the best probability of vanquishing your oponents, you should take the Arcane Comet, Manaflow Band, Transcendence, Scorch, Relentless Hunter, and Taste of Blood runes from the Sorcery and Domination rune sets. Out of all the rune sets players picked for Zyra and Lissandra pairings, this combo of runes resulted in the best win rate. In fact, these runes gave a 51.3% winrate overall.
By default, tips, statistics, and builds on how to team up Lissandra with Zyra are shown for all skill levels combined. To narrow the statistics and builds to an individual skill level, you may use the selection menu above.