Sleepy Trouble Bubble travels further over walls. Find a hiding spot to set up for a long distance kill.
Break Sleep with your biggest damage source, since enemies who are asleep take double damage.
Paddle Star deals more damage the further it has flown. Casting it behind yourself before redirecting can deal tons of damage.
Lay Waste is very strong at farming minions and harassing enemy champions.
Ask your allies to help point out when you should use Requiem to get kills in different lanes.
The Zoe Karthus synergy stats shown here demonstrate the areas of her gameplay that do better (or worse) when paired with Karthus, compared to her overall stats. Significant differences are areas of focus that highlight how her gameplay changes when paired with this other champion.
Overall, Zoe sees a very large drop in her KDA (ratio of kills and assists to deaths) when paired with Karthus. His KDA went down from NaN to NaN. This worsening shows that Karthus helps Zoe perform worse in competitive LoL rounds. Yet, the small difference indicates that this performance change is not very impactful.
When Zoe is an ally to Karthus, she observes a little increase in her total damage output. This difference could indicate that Karthus supports by providing cover for her to deal more damage or that his allyship also helps increase the game's duration. Similarly, when Zoe is played together with Karthus on the same team, he usually scores many fewer killing sprees than when she plays alone. This is contrasting evidence that she is worse when playing with Karthus.
Moreover, when Zoe plays with Karthus on the same side, she usually takes more damage than when she fights alone. Receiving more damage could mean that Karthus does a poor job of protecting Zoe during team fights.
There is no perfect champion pairing for Zoe that will 100% of the time be her ideal teammate. Yet, overall, Karthus is a very typical companion for Zoe. By being on the same side as Zoe, he drops their win rate by -0.6% to 46.4%. This proves that there is only a small bond between Zoe and Karthus that allows them to perform not as well together than alone.
Karthus has a greater difficulty than Zoe. That means you must be cautious when enlisting Karthus allies to play with, as they will need a greater level of skill to be able to work well with you.
Working on the same side, Zoe players should expect to witness an overall large increase in your team’s capability to to do a lot of AP damage. Combined, these two can blast through enemies with magic damage.
In contrast, by pairing Zoe and Karthus together, you may not be granting your team a great deal of attack damage. Make sure to pick other champions on your team that neutralizes this disparity in their abilities.
Regardless of the ability of your Karthus teammate, you need to focus on increasing your income, staying alive by avoiding foolish fights, and clearing objectives. If you heed this simple advice, you should do well, regardless.
If you would like to learn all of the intricacies of Zoe in order to synergize with Karthus during both the lane and mid / late game phases of League of Legends matches, you should keep reading to learn some more tricks and insights into this champion pairing. If you mind the build and suggestions displayed above, you will grow your win rate significantly.
The ideal items to have in your Zoe and Karthus synergy build include Rabadon's Deathcap, Stormsurge, and Luden's Companion. When Zoe incorporated at least these three items in her build, she did significantly better when fighting alongside Karthus than with many other common builds. In fact, Zoe boasted an average winrate of 46.4% helping carry Karthus with these items in her kit.
To have the best chance of crushing your oponents, you should equip the Electrocute, Taste of Blood, Eyeball Collection, Treasure Hunter, Manaflow Band, and Scorch runes from the Domination and Sorcery rune sets. Of all the rune builds that we analyzed for Zoe and Karthus pairings, this order of runes yielded the top win rate. In fact, these runes provided a 46.4% win rate overall.
If you would like to view Zoe and Karthus cooperations tips and stats for a a distinct division rank, feel free to select one from the selection menu displayed above. By default, the stats and guides displayed are computed using all rounds run with both champs.