Time Warp is an effective way to enable allies to finish off enemies, or escape from a losing battle.
Chronoshift is a powerful deterrent to attacking your carries, but casting Chronoshift too early in a fight can cause the enemy to switch targets too soon, making it less effective.
You can combine the use of Time Bomb and Rewind to place two Time Bombs on a target quickly. Placing the second bomb will detonate the first and stun all nearby enemies.
Don't go in first to a large teamfight. Wait for your teammates to initiate.
Tumble has many uses, but it cannot pass over walls.
Condemn can be used to both pin targets to walls to ensure a kill, or to escape a pursuer.
The Zilean Vayne synergy stats shown here demonstrate the areas of his gameplay that do better (or worse) when paired with Vayne, compared to his overall stats. Significant differences are areas of focus that highlight how his gameplay changes when paired with this other champion.
Overall, Zilean sees a large worsening in his KDA (ratio of kills and assists to deaths) when paired with Vayne. His KDA decreased from NaN to NaN. This negative change shows that Vayne helps Zilean perform worse in competitive League rounds. Yet, the small difference shows that this performance change is only marginal.
When Zilean is an ally to Vayne, he sees a marginal improvement in his full damage dealt. This change could indicate that Vayne supports by providing cover for him to deal more damage or that her presence also helps extend the match's duration. Similarly, when Zilean is played with Vayne on the same side, he usually scores many fewer killing sprees than when he plays alone. This is contrasting evidence that he is worse when playing with Vayne.
Additionally, when Zilean plays with Vayne on the same team, he often receives a little less damage than when he plays alone. Taking not as much damage could indicate that Vayne does a decent job of protecting Zilean during teamfights.
There is no one best companion for Zilean that will 100% of the time be his #1 teammate. However, overall, Vayne is a decent companion for Zilean. By being on the same team as Zilean, she raises their win rate by 2.1% to 52.8%. This signals that there is a good bond between Zilean and Vayne that results in them performing better together than alone.
Vayne has a greater difficulty than Zilean. That means you must be very careful when enlisting Vayne comrades to play with, as they will have to have a greater level of skill to do well with you.
Fighting on the same side, you should expect to witness an overall large increase in your team’s capability to deal physical damage. When paired, these champions can provide a great amount of sustained physical damage.
Although, by grouping Zilean and Vayne together, you probably will not be providing your other allies a great deal of protection for burst damage. We recommend you have other champs on your team that nullifies this gap in their playstyle.
Regardless of your Vayne ally's ability, you should focus on increasing your gold income, warding to avoid ambushes, and taking down objectives. If you do this, you should do well anyway.
To truly master Zilean to pair well with Vayne during both the early game and mid / late game phases of LoL, you should keep reading to master a few extra lessons on this champion pairing. If you use the build and suggestions shown here, you should increase your win rate significantly.
The top finished items to prioritize in your Zilean and Vayne synergy build include Shurelya's Battlesong, Solstice Sleigh, and Cosmic Drive. When Zilean combined at least these three pieces in his build, he performed much better as an ally of Vayne than with many other commonly used item sets. In fact, Zilean boasted an average winrate of 52.8% when playing alongside Vayne with this build.
To have the best likelihood of beating your oponents, Zilean players should take the Summon Aery, Manaflow Band, Transcendence, Scorch, Biscuit Delivery, and Cosmic Insight runes from the Sorcery and Inspiration rune sets. Of all the rune combinations players used for this champion pairing, this mix of runes resulted in the highest win rate. Moreover, these runes provided a 52.8% win rate overall.
If you would like to view Zilean with Vayne collaboration tips and stats for a a specific player tier, please choose one from the selection menu provided above. If viewing for the first time, the statistics and strategies shown are calculated using all games with data with these champions.