Time Warp is an effective way to enable allies to finish off enemies, or escape from a losing battle.
Chronoshift is a powerful deterrent to attacking your carries, but casting Chronoshift too early in a fight can cause the enemy to switch targets too soon, making it less effective.
You can combine the use of Time Bomb and Rewind to place two Time Bombs on a target quickly. Placing the second bomb will detonate the first and stun all nearby enemies.
Contaminate has a large range; apply as many stacks of Deadly Venom as possible before using it.
You can catch up to an enemy out of attack range with Venom Cask.
Twitch's Attack Speed is among the highest in the game; try purchasing items with on-hit effects such as Black Cleaver or Wit's End.
The Zilean Twitch synergy stats shown here demonstrate the areas of his gameplay that do better (or worse) when paired with Twitch, compared to his overall stats. Significant differences are areas of focus that highlight how his gameplay changes when paired with this other champion.
Overall, Zilean sees a large worsening in his KDA (ratio of kills and assists to deaths) when paired with Twitch. His KDA fell from NaN to NaN. This worsening shows that Twitch helps Zilean perform worse in ranked League of Legends games. Yet, the small difference proves that this performance change is only marginal.
When Zilean is an ally to Twitch, he sees a little decrease in his full damage output. This could signal that Twitch doesn't help cover for him to dish out more damage or that his allyship also helps extend the round's duration. Similarly, when Zilean is played alongside Twitch on the same team, he usually scores many fewer killing sprees compared to when he plays alone. This is contrasting evidence that he is worse when playing synergisticly with Twitch.
Additionally, when Zilean plays with Twitch on the same side, he often receives a little less damage than when he plays alone. Taking not as much damage could mean that Twitch does a decent job of protecting Zilean during teamfights.
There is no one best ally for Zilean that will no matter what be his best synergy. However, overall, Twitch is a very typical ally for Zilean. By being on the same side as Zilean, he increases their win rate by 0.3% to 51.0%. This shows that there is not really a strong bond between Zilean and Twitch that allows them to perform stronger together than alone.
Twitch has a lower difficulty than Zilean. That means Zilean players don't need to be cautious when finding Twitch comrades to play with, as they will need a relatively low level of skill to be able to work well with you.
Playing alongside, you should observe an overall large increase in your team’s capability to deal physical damage. Together, these champions can provide a great amount of sustained physical damage.
In contrast, by pairing Zilean and Twitch together, you may not be providing your other teammates much engage potential. Make sure to have other champs on your team that nullifies this relative disparity in their capabilities.
Regardless of your Twitch ally's ability, you need to focus on increasing your income, outlasting your enemies, and clearing objectives. If you do this, you will do well anyway.
If you would like to truly master Zilean in order to pair well with Twitch during both the laning and mid / late game phases of League, you should keep reading to gather additional lessons on this champion pairing. If you pay attention to the build and suggestions shown above, you will grow your win rate by a lot.
The ideal items to build first in your Zilean and Twitch synergy build include Shurelya's Battlesong, Morellonomicon, and Imperial Mandate. When Zilean bought at least these three great items in his build, he performed a lot better when fighting alongside Twitch than with many other common item sets. In fact, Zilean had an average winrate of 51.0% when synergizing his build and playstyle to Twitch with this build.
To have the highest likelihood of coming out on top against your oponents, you should equip the Summon Aery, Manaflow Band, Transcendence, Waterwalking, Cheap Shot, and Relentless Hunter runes from the Sorcery and Domination rune sets. Of all the rune combinations players picked for this champion pairing, this composite of runes resulted in the top win rate. In fact, these runes averaged a 51.0% win rate overall.
By default, tips, statistics, and builds on how to pair Twitch with Zilean are given for all skill levels, merged. To scope the stats and builds to a specific skill level, you can use the selection menu at the top of this page.