Time Warp is an effective way to enable allies to finish off enemies, or escape from a losing battle.
Chronoshift is a powerful deterrent to attacking your carries, but casting Chronoshift too early in a fight can cause the enemy to switch targets too soon, making it less effective.
You can combine the use of Time Bomb and Rewind to place two Time Bombs on a target quickly. Placing the second bomb will detonate the first and stun all nearby enemies.
Lay Waste is very strong at farming minions and harassing enemy champions.
Ask your allies to help point out when you should use Requiem to get kills in different lanes.
The Zilean Karthus synergy stats shown here demonstrate the areas of his gameplay that do better (or worse) when paired with Karthus, compared to his overall stats. Significant differences are areas of focus that highlight how his gameplay changes when paired with this other champion.
Overall, Zilean sees a large worsening in his KDA (ratio of kills and assists to deaths) when paired with Karthus. His KDA worsened from NaN to NaN. This worsening shows that Karthus helps Zilean perform worse in competitive League rounds. Yet, the small difference shows that this performance change is only marginal.
When Zilean is an ally to Karthus, he sees a small increase in his total damage output. This change could demonstrate that Karthus helps provide protection for him to dish out more damage or that his participation also helps extend the game's duration. Similarly, when Zilean is played alongside Karthus on the same team, he usually scores many fewer killing sprees than when he plays without Karthus. This is contrasting evidence that he is worse when playing alongside Karthus.
Moreover, when Zilean plays with Karthus on the same side, he usually receives much more damage than when he plays alone. Taking more damage could indicate that Karthus does a poor job of protecting Zilean during team fights.
There is no universally accepted best companion for Zilean that will always be his top ally. However, Karthus is a terrible companion for Zilean. By being on the same side as Zilean, he decreases their win rate by -7.2% to 43.5%. This demonstrates that there is a terrible synergy between Zilean and Karthus that results in them performing worse together than alone.
Karthus has a greater difficulty than Zilean. That means you should be cautious when finding Karthus allies to fight alongside, as they will have to have a greater level of skill to fight well with you.
When playing together, Zilean players should witness an overall large increase in your team’s capacity to deal magical damage. When paired, these champions can deal quite a lot of AP type damage.
In contrast, by aligning Zilean and Karthus together, you will not be granting your team much anti-tank damage dealing potential. Make sure to bring other champs on your team that offsets this relative gap in this pairing's potential.
Regardless of your Karthus ally's ability, you should focus on increasing your gold income, warding to avoid ambushes, and clearing objectives. If you heed this simple advice, you should do well, regardless.
If you would like to learn all of the intricacies of Zilean to pair well with Karthus during both the early game and mid / late game phases of LoL, you should continue reading to pick up additional lessons on this champion pairing. If you mind the build and suggestions presented above, you will grow your win rate significantly.
The most important finished items to prioritize in your Zilean and Karthus synergy build include Shurelya's Battlesong, Solstice Sleigh, and Imperial Mandate. When Zilean bought at least these three pieces in his build, he did a lot better when paired up with Karthus than with most other typical builds. In fact, Zilean boasted an average win rate of 43.5% when playing alongside Karthus with this build.
To have the highest chance of crushing your oponents, Zilean players should use the Summon Aery, Manaflow Band, Transcendence, Waterwalking, Cheap Shot, and Relentless Hunter runes from the Sorcery and Domination rune sets. Out of all the runes we have analyed for this champion pairing, this combination of runes resulted in the greatest win rate. In fact, these runes gave a 43.5% win rate overall.
If you want to get Zilean with Karthus cooperations tips and stats for a a particular skill level, feel free to select one from the selection menu displayed above. If viewing for the first time, the statistics and tips and suggestions given are computed using all matches run with both champs.