Don't go in first to a large teamfight. Wait for your teammates to initiate.
Tumble has many uses, but it cannot pass over walls.
Condemn can be used to both pin targets to walls to ensure a kill, or to escape a pursuer.
The Zeri Vayne synergy stats shown here demonstrate the areas of their gameplay that do better (or worse) when paired with Vayne, compared to their overall stats. Significant differences are areas of focus that highlight how their gameplay changes when paired with this other champion.
Overall, Zeri sees a very large drop in their KDA (ratio of kills and assists to deaths) when paired with Vayne. His KDA fell from NaN to NaN. This drop shows that Vayne helps Zeri perform poorer in ranked League of Legends rounds. Yet, the small difference indicates that this performance change is only marginal.
When Zeri plays on the same team as Vayne, they observes a marginal improvement in their full damage dealt. This change may demonstrate that Vayne helps provide cover for them to deal more damage or that her presence on the team also helps increase the game's duration. Similarly, when Zeri is played together with Vayne on the same side, he usually scores many fewer killing sprees than when they plays on his own. This is contrasting evidence that they is worse when playing synergisticly with Vayne.
Additionally, when Zeri plays with Vayne on the same team, they on average takes a little more damage than when they fights alone. Receiving more damage may mean that Vayne does a poor job of covering Zeri in team fights.
There is no perfect ally for Zeri that will 100% of the time be their best synergy. Yet, Vayne is a below average teammate for Zeri. By being on the same side as Zeri, she drops their win rate by -1.8% to 44.4%. This signals that there is a harmful synergy between Zeri and Vayne that results in them performing worse together than without each other.
Vayne has a greater difficulty than Zeri. That means you need to be cautious when lining up Vayne teammates to play with, as they will require a greater level of skill to play well with you.
Playing alongside, Zeri players will likely see an overall large increase in your team’s capacity to deal physical damage. Together, these champs can tear through the other team with a lot of physcial damage.
Conversely, by pairing Zeri and Vayne together, you probably will not be granting your team a lot of magic damage. Plan to include other champions on your team that helps cover this relative gap in their abilities.
Regardless of your Vayne ally's skill level, you need to focus on increasing your gold income, warding to avoid ambushes, and clearing objectives. If you do this, you should do well, regardless.
To truly master Zeri to work well with Vayne during both the laning and mid / late game phases of LoL matches, you should continue reading to gather some more tricks and insights into this champion pairing. If you pay attention to the build and suggestions presented above, you should grow your win rate by a lot.
The top items to build first in your Zeri and Vayne synergy build include Experimental Hexplate, Runaan's Hurricane, and Titanic Hydra. When Zeri included at least these three items in their build, they performed significantly better when fighting alongside Vayne than with most other common builds. In fact, Zeri had an average winrate of 44.4% helping carry Vayne with this build.
To have the highest probability of coming out on top against your oponents, Zeri players should use the Lethal Tempo, Triumph, Legend: Alacrity, Last Stand, Conditioning, and Overgrowth runes from the Precision and Resolve rune sets. Of all the runes players picked for Zeri and Vayne pairings, this blending of runes resulted in the top win rate. Notably, these runes averaged a 44.4% win rate overall.
By default, tips, stats, and builds on how to team up Vayne with Zeri are given for every ranked division. If you would like to filter the stats and builds to a particular rank, you may use the selection menu earlier on the page.