Lay Waste is very strong at farming minions and harassing enemy champions.
Ask your allies to help point out when you should use Requiem to get kills in different lanes.
The Zeri Karthus synergy stats shown here demonstrate the areas of their gameplay that do better (or worse) when paired with Karthus, compared to their overall stats. Significant differences are areas of focus that highlight how their gameplay changes when paired with this other champion.
Overall, Zeri sees a large worsening in their KDA (ratio of kills and assists to deaths) when paired with Karthus. His KDA went down from NaN to NaN. This drop shows that Karthus helps Zeri perform poorer in ranked League games. Yet, the small difference proves that this performance change is only marginal.
When Zeri is an ally to Karthus, they sees a little increase in their full damage dealt. This may signal that Karthus supports by providing protection for them to dish out more damage or that his allyship also helps increase the round's duration. Similarly, when Zeri is played together with Karthus on the same team, he usually scores many fewer killing sprees compared to when they plays without Karthus. This is contrasting evidence that they is worse when playing alongside Karthus.
Additionally, when Zeri plays with Karthus on the same side, they often takes more damage than when they fights alone. Getting dealt more damage may indicate that Karthus does a poor job of protecting Zeri in team fights.
There is no one best champion pairing for Zeri that will always be their best ally. Yet, Karthus is a relatively poor ally for Zeri. By playing on the same team as Zeri, he drops their win rate by -2.2% to 44.0%. This signals that there is a negative bond between Zeri and Karthus that results in them performing worse together than alone.
Karthus has a greater difficulty than Zeri. That means Zeri players need to be very careful when enlisting Karthus comrades to go into battle on the same side as, as they will need a greater level of skill to be able to work well with you.
Fighting alongside, you should witness an overall large increase in your team’s capability to deal magical damage. Combined, these two are able to dish out a surprising amount of magic type damage.
Conversely, by grouping Zeri and Karthus together, you may not be granting your team much tankyness. Make sure to have other champs on your team that neutralizes this hole in their abilities.
Regardless of your Karthus ally's ability, you should focus on maximizing your income, outlasting your enemies, and clearing objectives. If you do this, you should do well anyway.
If you would like to learn all of the intricacies of Zeri in order to pair well with Karthus during both the early game and mid / late game phases of LoL games, you should continue reading to gather a few extra tips and tricks for this champion pairing. If you listen to the build and tips presented here, you will grow your win rate by a lot.
The most crucial finished items to include in your Zeri and Karthus synergy build include Experimental Hexplate, Runaan's Hurricane, and Titanic Hydra. When Zeri included at least these three pieces in their build, they did much better when fighting alongside Karthus than with many other common builds. In fact, Zeri boasted an average win rate of 44.0% when playing alongside Karthus with this build.
To have the highest likelihood of annihilating your oponents, you should take the Lethal Tempo, Triumph, Legend: Alacrity, Last Stand, Conditioning, and Overgrowth runes from the Precision and Resolve rune sets. Out of all the runes that we analyzed for this champion pairing, this mix of runes resulted in the greatest win rate. Notably, these runes provided a 44.0% winrate overall.
If you would like to view Zeri with Karthus synergy tips and builds for a a specific rank, feel free to choose one from the selection menu displayed above. At first, the statistics and strategies shown are computed using every match played with these champs.