Lead your enemy when targeting with Noxious Blast to ensure the hit.
Use Twin Fang on poisoned stationary targets like monsters and units stunned by her Petrifying Gaze for maximum damage.
The Zeri Cassiopeia synergy stats shown here demonstrate the areas of their gameplay that do better (or worse) when paired with Cassiopeia, compared to their overall stats. Significant differences are areas of focus that highlight how their gameplay changes when paired with this other champion.
Overall, Zeri sees a very large drop in their KDA (ratio of kills and assists to deaths) when paired with Cassiopeia. His KDA fell from NaN to NaN. This worsening shows that Cassiopeia helps Zeri perform not as well in competitive League matches. Yet, the small difference proves that this performance change is not very impactful.
When Zeri is an ally to Cassiopeia, they gets a marginal improvement in their full damage dealt. This could indicate that Cassiopeia provides cover for them to deal more damage or that her presence on the team also helps increase the game's duration. Similarly, when Zeri is played alongside Cassiopeia on the same team, he usually scores many fewer killing sprees compared to when they plays alone. This is contrasting evidence that they is worse when playing synergisticly with Cassiopeia.
Additionally, when Zeri plays with Cassiopeia on the same side, they often takes a little more damage than when they fights alone. Getting dealt more damage could indicate that Cassiopeia does a poor job of protecting Zeri during teamfights.
There is no universally accepted best champion pairing for Zeri that will always be their ideal synergy. However, overall, Cassiopeia is a very bad companion for Zeri. By locking into the same side as Zeri, she drops their win rate by -3.9% to 42.3%. This shows that there is a terrible strategic relationship between Zeri and Cassiopeia that results in them performing worse together than without each other.
Cassiopeia has a much greater difficulty compared to Zeri. That means Zeri players should be very careful when arranging Cassiopeia comrades to fight alongside, as they will have to have a much greater level of skill to be able to fight well with you.
Working on the same side, you should observe an overall large increase in your team’s capability to deal magical damage. Combined, these champs can deal quite a lot of AP type damage.
Although, by aligning Zeri and Cassiopeia together, you may not be granting your side much tankyness. We recommend you bring other champions on your team that fills this disparity in their capabilities.
Regardless of the ability of your Cassiopeia ally, you should focus on increasing your gold income, staying alive by avoiding foolish fights, and taking down objectives. If you heed this simple advice, you will do well, regardless.
If you would like to learn all of the intricacies of Zeri to work well with Cassiopeia during both the lane and mid / late game phases of League rounds, you should keep reading to gather additional tricks and insights into this champion pairing. If you use the build and stats presented here, you should increase your win rate significantly.
The top items to use in your Zeri and Cassiopeia synergy build include Experimental Hexplate, Runaan's Hurricane, and Titanic Hydra. When Zeri included at least these three great items in their build, they did significantly better as an ally of Cassiopeia than with many other common item sets. In fact, Zeri had an average winrate of 42.3% when synergizing their build and playstyle to Cassiopeia with this build.
To have the best chance of vanquishing your oponents, you should equip the Lethal Tempo, Triumph, Legend: Alacrity, Last Stand, Conditioning, and Overgrowth runes from the Precision and Resolve rune sets. Out of all the rune sets players used for Zeri and Cassiopeia pairings, this mixture of runes yielded the highest win rate. In fact, these runes provided a 42.3% win rate overall.
If you would like to see Zeri with Cassiopeia collaboration tips and stats for a an individual rank, feel free to select one from the selection menu displayed above. At first, the stats and strategies given are computed using all rounds played with these champs.