Transfusion instantly deals damage to the enemy before healing Vladimir, making it one of the best last hitting tools in the game.
Cast Hemoplague where it will afflict the most units.
Sanguine Pool pops incoming missiles, so it can be used to dodge disables.
Time Warp is an effective way to enable allies to finish off enemies, or escape from a losing battle.
Chronoshift is a powerful deterrent to attacking your carries, but casting Chronoshift too early in a fight can cause the enemy to switch targets too soon, making it less effective.
You can combine the use of Time Bomb and Rewind to place two Time Bombs on a target quickly. Placing the second bomb will detonate the first and stun all nearby enemies.
The Vladimir Zilean synergy stats shown here demonstrate the areas of his gameplay that do better (or worse) when paired with Zilean, compared to his overall stats. Significant differences are areas of focus that highlight how his gameplay changes when paired with this other champion.
Overall, Vladimir sees a very large drop in his KDA (ratio of kills and assists to deaths) when paired with Zilean. His KDA fell from NaN to NaN. This decrease shows that Zilean helps Vladimir perform poorer in ranked League of Legends matches. Yet, the small difference shows that this performance change is only marginal.
When Vladimir is paired with Zilean, he observes a small increase in his total damage output. This difference may indicate that Zilean provides cover for him to deal more damage or that his participation also helps extend the game's duration. Similarly, when Vladimir is played together with Zilean on the same team, he usually scores many fewer killing sprees than when he plays on his own. This is contrasting evidence that he is worse when playing with Zilean.
Moreover, when Vladimir plays with Zilean on the same team, he typically takes a little more damage than when he plays alone. Getting dealt more damage may indicate that Zilean does a poor job of covering Vladimir in teamfights.
There is no top companion for Vladimir that will no matter what be his best ally. Yet, Zilean is a top-tier companion for Vladimir. By locking into the same side as Vladimir, he raises their win rate by 3.1% to 53.1%. This signals that there is a strong strategic relationship between Vladimir and Zilean that allows them to perform stronger together than alone.
Zilean has a lower difficulty than Vladimir. That means you don't need to be very careful when enlisting Zilean comrades to play with, as they will require a relatively low level of skill to be able to cooperate well with you.
Playing cooperatively, Vladimir players should expect to witness an overall large increase in your team’s ability to deal magic damage. When paired, these champs can deal quite a lot of AP type damage.
Conversely, by bringing Vladimir and Zilean together, you will not be providing your other allies a great deal of anti-tank damage dealing potential. Make sure to bring other champions on your team that helps cover this gap in this pairing's potential.
Regardless of your Zilean ally's skill level, you should focus on increasing your income, staying alive by avoiding foolish fights, and taking down objectives. If you follow these simple suggestions, you will do well, regardless.
To truly master Vladimir to pair well with Zilean during both the lane and mid / late game phases of League of Legends rounds, you should keep reading to learn some more lessons on this champion pairing. If you mind the build and tips shown above, you should increase your win rate significantly.
The most crucial finished items to use in your Vladimir and Zilean synergy build include Cosmic Drive, Riftmaker, and Liandry's Torment. When Vladimir used at least these three great items in his build, he did much better as an ally of Zilean than with many other commonly used item sets. In fact, Vladimir had an average win rate of 53.1% when synergizing his build and playstyle to Zilean with these items in his kit.
To have the best chance of coming out on top against your oponents, you should use the Phase Rush, Nimbus Cloak, Transcendence, Gathering Storm, Magical Footwear, and Cosmic Insight runes from the Sorcery and Inspiration rune sets. Of all the runes players used for this champion pairing, this combo of runes resulted in the greatest win rate. Notably, these runes provided a 53.1% win rate overall.
By default, tips, statistics, and builds on how to synergize Zilean with Vladimir are shown for all skill levels, merged. If you want to scope the stats and builds to an individual division, you can use the selection menu earlier in the counter matchup guide.