Transfusion instantly deals damage to the enemy before healing Vladimir, making it one of the best last hitting tools in the game.
Cast Hemoplague where it will afflict the most units.
Sanguine Pool pops incoming missiles, so it can be used to dodge disables.
While ganking, consider aiming Dredge Line at nearby terrain and following it up with Riptide for a higher hit rate.
Riptide has a delayed blast timing on activation - you can use this while running away or when enemies are incoming to serve as a deterrent.
The Vladimir Nautilus synergy stats shown here demonstrate the areas of his gameplay that do better (or worse) when paired with Nautilus, compared to his overall stats. Significant differences are areas of focus that highlight how his gameplay changes when paired with this other champion.
Overall, Vladimir sees a large worsening in his KDA (ratio of kills and assists to deaths) when paired with Nautilus. His KDA went down from NaN to NaN. This decrease shows that Nautilus helps Vladimir perform poorer in competitive League games. Yet, the small difference proves that this performance change is only marginal.
When Vladimir is paired with Nautilus, he observes a little drop in his complete damage output. This change may indicate that Nautilus doesn't help cover for him to deal more damage or that his support also helps extend the match's duration. Similarly, when Vladimir is played alongside Nautilus on the same side, he usually scores many fewer killing sprees compared to when he plays without Nautilus. This is contrasting evidence that he is worse when playing alongside Nautilus.
Additionally, when Vladimir plays with Nautilus on the same team, he on average receives a little less damage than when he plays alone. Taking not as much damage may mean that Nautilus does a decent job of protecting Vladimir in team fights.
There is no universally accepted best champion pairing for Vladimir that will 100% of the time be his best ally. Yet, Nautilus is a relatively poor companion for Vladimir. By being on the same team as Vladimir, he decreases their win rate by -2.3% to 47.7%. This demonstrates that there is a bad bond between Vladimir and Nautilus that results in them performing not as well together than without each other.
Nautilus has a lower difficulty than Vladimir. That means Vladimir players don't need to be very careful when enlisting Nautilus comrades to fight alongside, as they will require a relatively low level of skill to fight well with you.
When playing on the same side, you should expect to witness an overall large increase in your team’s ability to to do a lot of AP damage. Together, these champions can blast through enemies with magic damage.
In contrast, by bringing Vladimir and Nautilus together, you probably will not be providing your other teammates a lot of anti-tank damage dealing potential. Plan to have other champs on your team that nullifies this gap in this pairing's potential.
Regardless of your Nautilus ally's skill level, you need to focus on maximizing your gold income, outlasting your enemies, and taking down objectives. If you heed this simple advice, you will do well, regardless.
To truly master Vladimir to synergize with Nautilus during both the early game and mid / late game phases of League games, you should continue reading to learn a few extra tips and tricks for this champion pairing. If you use the build and suggestions presented here, you will grow your win rate by a lot.
The ideal items to build first in your Vladimir and Nautilus synergy build include Rabadon's Deathcap, Void Staff, and Riftmaker. When Vladimir used at least these three items in his build, he performed much better when fighting alongside Nautilus than with most other common item sets. In fact, Vladimir had an average winrate of 47.7% when synergizing his build and playstyle to Nautilus with these items in his kit.
To have the highest likelihood of beating your oponents, Vladimir players should equip the Phase Rush, Nimbus Cloak, Transcendence, Gathering Storm, Magical Footwear, and Cosmic Insight runes from the Sorcery and Inspiration rune sets. Out of all the rune sets players chose for this champion pairing, this combination of runes yielded the greatest win rate. Moreover, these runes gave a 47.7% winrate overall.
If you want to see Vladimir and Nautilus cooperations tips and stats for a a specific skill level, feel free to choose one from the selection menu provided above. At first, the stats and strategies given are calculated using every match played with both champs.