Transfusion instantly deals damage to the enemy before healing Vladimir, making it one of the best last hitting tools in the game.
Cast Hemoplague where it will afflict the most units.
Sanguine Pool pops incoming missiles, so it can be used to dodge disables.
Lay Waste is very strong at farming minions and harassing enemy champions.
Ask your allies to help point out when you should use Requiem to get kills in different lanes.
The Vladimir Karthus synergy stats shown here demonstrate the areas of his gameplay that do better (or worse) when paired with Karthus, compared to his overall stats. Significant differences are areas of focus that highlight how his gameplay changes when paired with this other champion.
Overall, Vladimir sees a very large drop in his KDA (ratio of kills and assists to deaths) when paired with Karthus. His KDA worsened from NaN to NaN. This drop shows that Karthus helps Vladimir perform worse in competitive League of Legends games. Yet, the small difference demonstrates that this performance change is only marginal.
When Vladimir tries to synergize with Karthus, he sees a little decrease in his total damage output. This change may signal that Karthus does not provide protection for him to dish out more damage or that his allyship also helps increase the game's duration. Similarly, when Vladimir is played together with Karthus on the same team, he usually scores many fewer killing sprees than when he plays without Karthus. This is contrasting evidence that he is worse when playing alongside Karthus.
Moreover, when Vladimir plays with Karthus on the same side, he on average receives a little more damage than when he plays alone. Taking more damage may indicate that Karthus does a poor job of covering Vladimir in team fights.
There is no one best champion pairing for Vladimir that will no matter what be his ideal ally. Yet, Karthus is a below average teammate for Vladimir. By playing on the same team as Vladimir, he decreases their win rate by -2.9% to 47.1%. This proves that there is a harmful strategic relationship between Vladimir and Karthus that results in them performing not as well together than without each other.
Karthus has a lower difficulty than Vladimir. That means you don't need to be cautious when finding Karthus teammates to play with, as they will require a lower level of skill to fight well with you.
Fighting on the same side, you will likely see an overall large increase in your team’s ability to deal magical damage. Together, these champions can deal quite a lot of AP type damage.
In contrast, by grouping Vladimir and Karthus together, you may not be providing your team much sustained damage output. Plan to bring other champions on your team that fills this gap in their kit.
Regardless of the skill of your Karthus teammate, you need to focus on maximizing your income, staying alive by avoiding foolish fights, and clearing objectives. If you heed this simple advice, you should do well anyway.
To learn all of the intricacies of Vladimir to pair well with Karthus during both the early game and mid / late game phases of LoL games, you should continue reading to master additional tricks and insights into this champion pairing. If you mind the build and suggestions displayed here, you will grow your win rate by a lot.
The most important items to use in your Vladimir and Karthus synergy build include Cosmic Drive, Riftmaker, and Liandry's Torment. When Vladimir combined at least these three pieces in his build, he performed significantly better when fighting alongside Karthus than with many other typical item sets. In fact, Vladimir boasted an average win rate of 47.1% helping carry Karthus with this build.
To have the greatest likelihood of annihilating your oponents, Vladimir players should equip the Phase Rush, Nimbus Cloak, Transcendence, Gathering Storm, Magical Footwear, and Cosmic Insight runes from the Sorcery and Inspiration rune sets. Of all the rune sets players chose for Vladimir and Karthus pairings, this set of runes yielded the highest win rate. Notably, these runes averaged a 47.1% win rate overall.
If you would like to view Vladimir with Karthus collaboration tips and builds for a an individual player tier, please select one from the selection menu displayed above. If viewing for the first time, the stats and build suggestions displayed are calculated using every match run with both champions.