Transfusion instantly deals damage to the enemy before healing Vladimir, making it one of the best last hitting tools in the game.
Cast Hemoplague where it will afflict the most units.
Sanguine Pool pops incoming missiles, so it can be used to dodge disables.
Make sure to buy items that will evolve at least 1 or 2 of your spells.
Work with your teammates to set up your Ultimate and optimize damage with your passive.
Try to catch enemy carries alone to burst them with Icathian Rain.
The Vladimir Kai'Sa synergy stats shown here demonstrate the areas of his gameplay that do better (or worse) when paired with Kai'Sa, compared to his overall stats. Significant differences are areas of focus that highlight how his gameplay changes when paired with this other champion.
Overall, Vladimir sees a very large drop in his KDA (ratio of kills and assists to deaths) when paired with Kai'Sa. His KDA went down from NaN to NaN. This drop shows that Kai'Sa helps Vladimir perform not as well in ranked LoL matches. Yet, the small difference proves that this performance change is only marginal.
When Vladimir is paired with Kai'Sa, he sees a little drop in his complete damage output. This difference could indicate that Kai'Sa doesn't help protection for him to dish out more damage or that her presence on the team also helps increase the match's duration. Similarly, when Vladimir is played with Kai'Sa on the same side, he usually scores many fewer killing sprees than when he plays without Kai'Sa. This is contrasting evidence that he is worse when playing with Kai'Sa.
Moreover, when Vladimir plays with Kai'Sa on the same team, he on average receives a little less damage than when he plays alone. Receiving not as much damage may indicate that Kai'Sa does a decent job of protecting Vladimir in team fights.
There is no one best synergy for Vladimir that will always be his #1 ally. However, Kai'Sa is a very bad teammate for Vladimir. By locking into the same team as Vladimir, she decreases their win rate by -4.6% to 45.4%. This clearly indicates that there is a terrible bond between Vladimir and Kai'Sa that results in them performing worse together than alone.
Kai'Sa has a lower difficulty than Vladimir. That means you don't need to be careful when arranging Kai'Sa teammates to fight alongside, as they will require a relatively low level of skill to be able to cooperate well with you.
Working alongside, Vladimir players should observe an overall large increase in your team’s capacity to to do a lot of AP damage. Combined, these champs are able to dish out a surprising amount of magic type damage.
Conversely, by grouping Vladimir and Kai'Sa together, you probably will not be providing your team a great deal of utility. Make sure to bring other champs on your team that nullifies this hole in their abilities.
Regardless of the skill of your Kai'Sa ally, you should focus on increasing your income, warding to avoid ambushes, and taking down objectives. If you heed this simple advice, you will do well, regardless.
If you would like to truly master Vladimir in order to synergize with Kai'Sa during both the laning and mid / late game phases of LoL matches, you should continue reading to pick up a few extra tips and tricks for this champion pairing. If you mind the build and stats displayed here, you should grow your win rate by a lot.
The ideal finished items to focus on in your Vladimir and Kai'Sa synergy build include Rabadon's Deathcap, Zhonya's Hourglass, and Riftmaker. When Vladimir included at least these three great items in his build, he did significantly better when paired up with Kai'Sa than with most other commonly used builds. In fact, Vladimir boasted an average win rate of 45.4% helping carry Kai'Sa with these items in his kit.
To have the greatest chance of coming out on top against your oponents, Vladimir players should take the Phase Rush, Nimbus Cloak, Transcendence, Gathering Storm, Magical Footwear, and Cosmic Insight runes from the Sorcery and Inspiration rune sets. Out of all the runes players picked for Vladimir and Kai'Sa pairings, this composite of runes resulted in the highest win rate. Moreover, these runes gave a 45.4% win rate overall.
If you need to get Vladimir and Kai'Sa cooperations tips and builds for a a particular skill level, feel free to select one from the selection menu above. By default, the statistics and tips and suggestions displayed are computed using all matches run with these champions.