Transfusion instantly deals damage to the enemy before healing Vladimir, making it one of the best last hitting tools in the game.
Cast Hemoplague where it will afflict the most units.
Sanguine Pool pops incoming missiles, so it can be used to dodge disables.
Molten Shield is a good spell to cast to work up to Annie's stun, so sometimes it's beneficial to grab at least 1 rank in it early.
Striking killing blows on minions with Disintegrate enables Annie to farm extremely well early in the game.
Storing a stun for use with her ultimate can turn the tide of a team fight.
The Vladimir Annie synergy stats shown here demonstrate the areas of his gameplay that do better (or worse) when paired with Annie, compared to his overall stats. Significant differences are areas of focus that highlight how his gameplay changes when paired with this other champion.
Overall, Vladimir sees a large worsening in his KDA (ratio of kills and assists to deaths) when paired with Annie. His KDA worsened from NaN to NaN. This negative change shows that Annie helps Vladimir perform worse in competitive League matches. Yet, the small difference demonstrates that this performance change is only marginal.
When Vladimir tries to synergize with Annie, he observes a small decrease in his total damage output. This difference could demonstrate that Annie does not help protection for him to deal more damage or that her presence also helps increase the round's duration. Similarly, when Vladimir is played together with Annie on the same side, he usually scores many fewer killing sprees compared to when he plays alone. This is contrasting evidence that he is worse when playing alongside Annie.
Additionally, when Vladimir plays with Annie on the same side, he on average receives a little more damage than when he fights alone. Getting dealt more damage may indicate that Annie does a poor job of protecting Vladimir during team fights.
There is no universally accepted best synergy for Vladimir that will 100% of the time be his #1 synergy. Yet, Annie is a very bad ally for Vladimir. By locking into the same team as Vladimir, she decreases their win rate by -7.3% to 42.7%. This clearly indicates that there is a very bad synergy between Vladimir and Annie that allows them to perform worse together than alone.
Annie has a lower difficulty than Vladimir. That means Vladimir players don't need to be very careful when arranging Annie allies to play with, as they will have to have a relatively low level of skill to be able to do well with you.
Working on the same side, Vladimir players should witness an overall large increase in your team’s ability to deal magical damage. Together, these champs can blast through enemies with magic damage.
Conversely, by grouping Vladimir and Annie together, you will not be giving your side a lot of AD. Make sure to have other champs on your team that nullifies this relative hole in their potential.
Regardless of the skill of your Annie teammate, you should focus on increasing your income, outlasting your enemies, and clearing objectives. If you heed this simple advice, you will do well, regardless.
To learn all of the intricacies of Vladimir in order to synergize with Annie during both the lane and mid / late game phases of League of Legends matches, you should keep reading to learn some more tips and tricks for this champion pairing. If you pay attention to the build and stats displayed here, you should increase your win rate by a lot.
The best items to use in your Vladimir and Annie synergy build include Rabadon's Deathcap, Riftmaker, and Liandry's Torment. When Vladimir used at least these three finished items in his build, he performed significantly better as an ally of Annie than with many other commonly used item sets. In fact, Vladimir had an average winrate of 42.7% helping carry Annie with these items in his kit.
To have the highest chance of beating your oponents, Vladimir players should equip the Phase Rush, Nimbus Cloak, Transcendence, Gathering Storm, Cosmic Insight, and Magical Footwear runes from the Sorcery and Inspiration rune sets. Of all the rune builds players picked for Vladimir and Annie pairings, this sequence of runes yielded the highest win rate. Notably, these runes averaged a 42.7% win rate overall.
By default, tips, stats, and builds on how to team up Annie with Vladimir are displayed for all skill levels, merged. To narrow the stats and builds to a distinct division, you may use the selection menu earlier on the page.