Lay Waste is very strong at farming minions and harassing enemy champions.
Ask your allies to help point out when you should use Requiem to get kills in different lanes.
The Vex Karthus synergy stats shown here demonstrate the areas of their gameplay that do better (or worse) when paired with Karthus, compared to their overall stats. Significant differences are areas of focus that highlight how their gameplay changes when paired with this other champion.
Overall, Vex sees a very large drop in their KDA (ratio of kills and assists to deaths) when paired with Karthus. His KDA went down from NaN to NaN. This fall shows that Karthus helps Vex perform poorer in ranked League of Legends matches. Yet, the small difference proves that this performance change is only marginal.
When Vex is an ally to Karthus, they gets a small decrease in their full damage dealt. This change may indicate that Karthus does not provide protection for them to deal more damage or that his allyship also helps extend the match's duration. Similarly, when Vex is played together with Karthus on the same team, he usually scores many fewer killing sprees than when they plays without Karthus. This is contrasting evidence that they is worse when playing with Karthus.
Additionally, when Vex plays with Karthus on the same team, they often takes a little more damage than when they plays alone. Taking more damage may mean that Karthus does a poor job of covering Vex during teamfights.
There is no perfect synergy for Vex that will always be their #1 ally. Yet, Karthus is a terrible companion for Vex. By being on the same side as Vex, he drops their win rate by -3.4% to 45.4%. This signals that there is a terrible synergy between Vex and Karthus that results in them performing not as well together than without each other.
Karthus has a much greater difficulty compared to Vex. That means you need to be careful when enlisting Karthus comrades to fight alongside, as they will have to have a much higher level of skill to play well with you.
When playing together, you will likely see an overall large increase in your team’s capability to to do a lot of AP damage. Combined, these champs are able to dish out a surprising amount of magic type damage.
In contrast, by bringing Vex and Karthus together, you will not be granting your other allies very much sustained damage output. Plan to have other champions on your team that offsets this relative hole in their playstyle.
Regardless of your Karthus ally's skill level, you need to focus on maximizing your income, staying alive by avoiding foolish fights, and taking down objectives. If you follow these simple suggestions, you will do well, regardless.
To truly master Vex in order to work well with Karthus during both the lane and mid / late game phases of League of Legends matches, you should keep reading to learn a few extra tips and tricks for this champion pairing. If you use the build and stats shown here, you will grow your win rate significantly.
The most crucial items to use in your Vex and Karthus synergy build include Rabadon's Deathcap, Stormsurge, and Luden's Companion. When Vex incorporated at least these three items in their build, they did significantly better when fighting alongside Karthus than with many other common builds. In fact, Vex boasted an average win rate of 45.4% helping carry Karthus with this build.
To have the greatest chance of vanquishing your oponents, Vex players should take the Electrocute, Taste of Blood, Eyeball Collection, Ultimate Hunter, Manaflow Band, and Transcendence runes from the Domination and Sorcery rune sets. Of all the rune builds we have analyed for this team composition, this mixture of runes resulted in the greatest win rate. Notably, these runes gave a 45.4% winrate overall.
By default, tips, stats, and builds on how to pair Karthus with Vex are shown for every ranked division. To scope the stats and builds to a particular division, you should use the selection menu located at the top of this page.