Be very careful about when to use Life Form Disintegration Ray. Many champions have abilities that can interrupt the spell.
Shooting Plasma Fission diagonally and splitting at maximum range allows you to hit opponents that are out of the range of the initial missile, but is more challenging to pull off.
When laning, use Void Rift to kill minions while building stacks of Organic Deconstruction on your opponent. You can then follow up with your other abilities.
Don't go in first to a large teamfight. Wait for your teammates to initiate.
Tumble has many uses, but it cannot pass over walls.
Condemn can be used to both pin targets to walls to ensure a kill, or to escape a pursuer.
The Vel'Koz Vayne synergy stats shown here demonstrate the areas of his gameplay that do better (or worse) when paired with Vayne, compared to his overall stats. Significant differences are areas of focus that highlight how his gameplay changes when paired with this other champion.
Overall, Vel'Koz sees a large worsening in his KDA (ratio of kills and assists to deaths) when paired with Vayne. His KDA worsened from NaN to NaN. This drop shows that Vayne helps Vel'Koz perform worse in ranked League of Legends rounds. Yet, the small difference shows that this performance change is only marginal.
When Vel'Koz plays on the same team as Vayne, he gets a small increase in his complete damage dealt. This difference may demonstrate that Vayne supports by providing cover for him to dish out more damage or that her support also helps extend the game's duration. Similarly, when Vel'Koz is played with Vayne on the same team, he usually scores many fewer killing sprees compared to when he plays without Vayne. This is contrasting evidence that he is worse when playing alongside Vayne.
Moreover, when Vel'Koz plays with Vayne on the same team, he often receives a little less damage than when he plays alone. Taking not as much damage may mean that Vayne does a decent job of protecting Vel'Koz during team fights.
There is no perfect ally for Vel'Koz that will always be his top ally. However, Vayne is a good teammate for Vel'Koz. By playing on the same side as Vel'Koz, she raises their win rate by 1.8% to 52.1%. This shows that there is a somewhat important bond between Vel'Koz and Vayne that results in them performing at the top of their game together than alone.
Vayne has a lower difficulty than Vel'Koz. That means Vel'Koz players don't need to be careful when arranging Vayne allies to play with, as they will require a relatively low level of skill to cooperate well with you.
Working on the same side, Vel'Koz players should observe an overall large increase in your team’s capacity to dish out massive AD. Combined, these champions should be able to take down targets with auto-attacks and other AD damage abilities.
In contrast, by bringing Vel'Koz and Vayne together, you may not be providing your other allies enough engage potential. Plan to bring other champions on your team that nullifies this hole in this pairing's abilities.
Regardless of your Vayne ally's ability, you should focus on increasing your income, outlasting your enemies, and taking down objectives. If you follow these simple suggestions, you should do well, regardless.
To learn all of the intricacies of Vel'Koz to pair well with Vayne during both the lane and mid / late game phases of League matches, you should keep reading to gather additional tricks and insights into this champion pairing. If you mind the build and tips displayed above, you should increase your win rate significantly.
The best items to have in your Vel'Koz and Vayne synergy build consist of Rabadon's Deathcap, Malignance, and Shadowflame. When Vel'Koz bought at least these three great items in his build, he performed a lot better as an ally of Vayne than with most other commonly used item sets. In fact, Vel'Koz had an average win rate of 52.1% helping carry Vayne with these items in his kit.
To have the best probability of beating your oponents, Vel'Koz players should use the Dark Harvest, Cheap Shot, Ghost Poro, Relentless Hunter, Manaflow Band, and Scorch runes from the Domination and Sorcery rune sets. Of all the rune sets players picked for Vel'Koz and Vayne pairings, this order of runes yielded the best win rate. Notably, these runes provided a 52.1% win rate overall.
By default, tips, statistics, and builds on how to synergize Vayne with Vel'Koz are shown for every ranked division. To narrow the statistics and builds to a distinct division, you can use the selection menu located at the top of this page.