Don't go in first to a large teamfight. Wait for your teammates to initiate.
Tumble has many uses, but it cannot pass over walls.
Condemn can be used to both pin targets to walls to ensure a kill, or to escape a pursuer.
Sleepy Trouble Bubble travels further over walls. Find a hiding spot to set up for a long distance kill.
Break Sleep with your biggest damage source, since enemies who are asleep take double damage.
Paddle Star deals more damage the further it has flown. Casting it behind yourself before redirecting can deal tons of damage.
The Vayne Zoe synergy stats shown here demonstrate the areas of her gameplay that do better (or worse) when paired with Zoe, compared to her overall stats. Significant differences are areas of focus that highlight how her gameplay changes when paired with this other champion.
Overall, Vayne sees a very large drop in her KDA (ratio of kills and assists to deaths) when paired with Zoe. His KDA worsened from NaN to NaN. This drop shows that Zoe helps Vayne perform not as well in competitive LoL games. Yet, the small difference shows that this performance change is only marginal.
When Vayne tries to synergize with Zoe, she observes a barely noticable drop in her total damage dealt. This change could indicate that Zoe does not support by providing protection for her to dish out more damage or that her presence on the team also helps increase the game's duration. Similarly, when Vayne is played together with Zoe on the same team, he usually scores many fewer killing sprees compared to when she plays on his own. This is contrasting evidence that she is worse when playing alongside Zoe.
Moreover, when Vayne plays with Zoe on the same side, she usually receives a little more damage than when she fights alone. Receiving more damage could mean that Zoe does a poor job of protecting Vayne in teamfights.
There is no top synergy for Vayne that will no matter what be her #1 teammate. Yet, overall, Zoe is a below average companion for Vayne. By locking into the same side as Vayne, she drops their win rate by -2.5% to 47.8%. This demonstrates that there is a harmful strategic relationship between Vayne and Zoe that results in them performing not as well together than alone.
Zoe has a much lower diffuclty than Vayne. That means you don't need to be careful when finding Zoe allies to go into battle on the same side as, as they will require a much lower level of skill to be able to cooperate well with you.
Working alongside, you should see an overall large increase in your team’s capacity to dish out massive AD. Together, these champions can provide a great amount of sustained physical damage.
Conversely, by aligning Vayne and Zoe together, you will not be granting your side a great deal of utility. Make sure to include other champions on your team that offsets this relative disparity in this pairing's abilities.
Regardless of the skill of your Zoe teammate, you need to focus on maximizing your income, staying alive by avoiding foolish fights, and taking down objectives. If you heed this simple advice, you will do well, regardless.
If you would like to truly master Vayne in order to synergize with Zoe during both the lane and mid / late game phases of League of Legends games, you should keep reading to master additional lessons on this champion pairing. If you mind the build and tips displayed above, you will grow your win rate by a lot.
The ideal finished items to have in your Vayne and Zoe synergy build include Wit's End, Guinsoo's Rageblade, and Kraken Slayer. When Vayne incorporated at least these three great items in her build, she did much better when paired up with Zoe than with many other typical builds. In fact, Vayne boasted an average winrate of 47.8% when playing alongside Zoe with this build.
To have the greatest chance of annihilating your oponents, you should use the Lethal Tempo, Triumph, Legend: Alacrity, Coup de Grace, Conditioning, and Overgrowth runes from the Precision and Resolve rune sets. Of all the rune combinations that we analyzed for Vayne and Zoe pairings, this mixture of runes yielded the best win rate. Notably, these runes gave a 47.8% winrate overall.
By default, tips, statistics, and builds on how to pair Zoe with Vayne are shown for all skill levels combined. If you would like to filter the statistics and builds to a particular division, you may use the selection menu located at the top of this page.