Don't go in first to a large teamfight. Wait for your teammates to initiate.
Tumble has many uses, but it cannot pass over walls.
Condemn can be used to both pin targets to walls to ensure a kill, or to escape a pursuer.
Time Warp is an effective way to enable allies to finish off enemies, or escape from a losing battle.
Chronoshift is a powerful deterrent to attacking your carries, but casting Chronoshift too early in a fight can cause the enemy to switch targets too soon, making it less effective.
You can combine the use of Time Bomb and Rewind to place two Time Bombs on a target quickly. Placing the second bomb will detonate the first and stun all nearby enemies.
The Vayne Zilean synergy stats shown here demonstrate the areas of her gameplay that do better (or worse) when paired with Zilean, compared to her overall stats. Significant differences are areas of focus that highlight how her gameplay changes when paired with this other champion.
Overall, Vayne sees a very large drop in her KDA (ratio of kills and assists to deaths) when paired with Zilean. His KDA worsened from NaN to NaN. This worsening shows that Zilean helps Vayne perform poorer in ranked League of Legends rounds. Yet, the small difference indicates that this performance change is not very impactful.
When Vayne plays on the same team as Zilean, she sees a small increase in her complete damage dealt. This could demonstrate that Zilean supports by providing protection for her to dish out more damage or that his participation also helps extend the round's duration. Similarly, when Vayne is played alongside Zilean on the same team, he usually scores many fewer killing sprees compared to when she plays alone. This is contrasting evidence that she is worse when playing with Zilean.
Additionally, when Vayne plays with Zilean on the same team, she typically takes more damage than when she fights alone. Taking more damage may indicate that Zilean does a poor job of covering Vayne in teamfights.
There is no ideal champion pairing for Vayne that will no matter what be her #1 ally. Yet, overall, Zilean is a good ally for Vayne. By being on the same side as Vayne, he raises their win rate by 2.5% to 52.8%. This shows that there is a potentially meaningful strategic relationship between Vayne and Zilean that results in them performing stronger together than without each other.
Zilean has a lower difficulty than Vayne. That means you don't need to be very careful when lining up Zilean allies to go into battle on the same side as, as they will require a lower level of skill to do well with you.
Playing alongside, Vayne players should expect to observe an overall large increase in your team’s capability to dish out massive AD. When paired, these two should be able to take down targets with auto-attacks and other AD damage abilities.
In contrast, by pairing Vayne and Zilean together, you probably will not be granting your other teammates enough engage potential. We recommend you include other champions on your team that helps cover this hole in this pairing's kit.
Regardless of your Zilean ally's ability, you need to focus on maximizing your gold income, outlasting your enemies, and taking down objectives. If you heed this simple advice, you should do well anyway.
If you would like to truly master Vayne in order to pair well with Zilean during both the laning and mid / late game phases of LoL rounds, you should keep reading to master some more tricks and insights into this champion pairing. If you mind the build and suggestions shown above, you will grow your win rate significantly.
The best items to have in your Vayne and Zilean synergy build include Wit's End, Guinsoo's Rageblade, and Terminus. When Vayne used at least these three pieces in her build, she performed a lot better when paired up with Zilean than with many other common item sets. In fact, Vayne had an average winrate of 52.8% when synergizing her build and playstyle to Zilean with this build.
To have the greatest chance of crushing your oponents, Vayne players should use the Lethal Tempo, Triumph, Legend: Alacrity, Coup de Grace, Conditioning, and Overgrowth runes from the Precision and Resolve rune sets. Of all the rune combinations we have analyed for this champion pairing, this mix of runes yielded the highest win rate. Moreover, these runes provided a 52.8% winrate overall.
If you would like to view Vayne with Zilean cooperations tips and builds for a an individual division, feel free to select one from the selection menu provided above. At first, the statistics and strategies given are computed using every game run with these champions.