Don't go in first to a large teamfight. Wait for your teammates to initiate.
Tumble has many uses, but it cannot pass over walls.
Condemn can be used to both pin targets to walls to ensure a kill, or to escape a pursuer.
The Vayne Sett synergy stats shown here demonstrate the areas of her gameplay that do better (or worse) when paired with Sett, compared to her overall stats. Significant differences are areas of focus that highlight how her gameplay changes when paired with this other champion.
Overall, Vayne sees a large worsening in her KDA (ratio of kills and assists to deaths) when paired with Sett. His KDA fell from NaN to NaN. This decrease shows that Sett helps Vayne perform poorer in ranked LoL rounds. Yet, the small difference demonstrates that this performance change is not very impactful.
When Vayne tries to synergize with Sett, she gets a small decrease in her full damage dealt. This difference may signal that Sett does not provide protection for her to deal more damage or that his presence on the team also helps extend the match's duration. Similarly, when Vayne is played with Sett on the same side, he usually scores many fewer killing sprees compared to when she plays on his own. This is contrasting evidence that she is worse when playing with Sett.
Moreover, when Vayne plays with Sett on the same side, she usually receives a little less damage than when she plays alone. Receiving not as much damage could mean that Sett does a decent job of covering Vayne in team fights.
There is no top synergy for Vayne that will no matter what be her top ally. Yet, overall, Sett is a good teammate for Vayne. By being on the same side as Vayne, he raises their win rate by 1.5% to 51.8%. This clearly indicates that there is a potentially meaningful bond between Vayne and Sett that results in them performing stronger together than without each other.
Sett has a much lower diffuclty than Vayne. That means you don't need to be cautious when lining up Sett teammates to fight alongside, as they will need a much lower level of skill to fight well with you.
Working on the same side, you should expect to witness an overall large increase in your team’s capacity to deal physical damage. Combined, these two should be able to take down targets with auto-attacks and other AD damage abilities.
In contrast, by bringing Vayne and Sett together, you probably will not be granting your other teammates very much magical damage output. We recommend you include other champs on your team that neutralizes this hole in their playstyle.
Regardless of the skill of your Sett ally, you should focus on maximizing your income, warding to avoid ambushes, and taking down objectives. If you do this, you will do well anyway.
If you would like to learn all of the intricacies of Vayne in order to pair well with Sett during both the lane and mid / late game phases of LoL matches, you should keep reading to pick up a few extra lessons on this champion pairing. If you mind the build and stats displayed here, you will grow your win rate significantly.
The best finished items to focus on in your Vayne and Sett synergy build include Guardian Angel, Wit's End, and Blade of The Ruined King. When Vayne bought at least these three great items in her build, she performed much better when paired up with Sett than with many other commonly used builds. In fact, Vayne boasted an average winrate of 51.8% helping carry Sett with these items in her kit.
To have the greatest probability of coming out on top against your oponents, you should use the Lethal Tempo, Triumph, Legend: Alacrity, Coup de Grace, Conditioning, and Overgrowth runes from the Precision and Resolve rune sets. Of all the rune builds players picked for this champion pairing, this mix of runes yielded the top win rate. In fact, these runes gave a 51.8% win rate overall.
By default, tips, statistics, and builds on how to pair Sett with Vayne are displayed for all ranked divisions. If you would like to scope the statistics and builds to a distinct player tier, you may use the selection menu located earlier in the counter matchup guide.