Don't go in first to a large teamfight. Wait for your teammates to initiate.
Tumble has many uses, but it cannot pass over walls.
Condemn can be used to both pin targets to walls to ensure a kill, or to escape a pursuer.
The Vayne Seraphine synergy stats shown here demonstrate the areas of her gameplay that do better (or worse) when paired with Seraphine, compared to her overall stats. Significant differences are areas of focus that highlight how her gameplay changes when paired with this other champion.
Overall, Vayne sees a large worsening in her KDA (ratio of kills and assists to deaths) when paired with Seraphine. His KDA fell from NaN to NaN. This fall shows that Seraphine helps Vayne perform poorer in competitive League of Legends rounds. Yet, the small difference proves that this performance change is not very impactful.
When Vayne is an ally to Seraphine, she gets a small increase in her complete damage dealt. This could demonstrate that Seraphine provides cover for her to dish out more damage or that her allyship also helps increase the game's duration. Similarly, when Vayne is played together with Seraphine on the same side, he usually scores many fewer killing sprees than when she plays alone. This is contrasting evidence that she is worse when playing with Seraphine.
Moreover, when Vayne plays with Seraphine on the same team, she usually receives a little less damage than when she plays alone. Taking not as much damage could mean that Seraphine does a decent job of protecting Vayne during teamfights.
There is no one best ally for Vayne that will always be her top ally. Yet, Seraphine is a below average companion for Vayne. By locking into the same team as Vayne, she lowers their win rate by -1.6% to 48.7%. This demonstrates that there is a negative strategic relationship between Vayne and Seraphine that results in them performing worse together than without each other.
Seraphine has a much lower diffuclty than Vayne. That means you don't need to be very careful when enlisting Seraphine teammates to fight alongside, as they will have to have a much lower level of skill to be able to play well with you.
Playing together, Vayne players should expect to see an overall large increase in your team’s capability to provide a lot of utility for your team. When paired, these champions may be able to carry with the power of their abilities.
Although, by aligning Vayne and Seraphine together, you will not be granting your side very much AP. We recommend you bring other champions on your team that nullifies this hole in their kit.
Regardless of the skill of your Seraphine ally, you should focus on maximizing your gold income, warding to avoid ambushes, and clearing objectives. If you follow these simple suggestions, you will do well anyway.
If you would like to truly master Vayne to work well with Seraphine during both the early game and mid / late game phases of LoL matches, you should keep reading to gather some more tricks and insights into this champion pairing. If you pay attention to the build and stats displayed here, you should increase your win rate by a lot.
The most crucial items to have in your Vayne and Seraphine synergy build include Wit's End, Terminus, and Kraken Slayer. When Vayne combined at least these three pieces in her build, she performed much better as an ally of Seraphine than with most other typical item sets. In fact, Vayne had an average winrate of 48.7% when playing alongside Seraphine with these items in her kit.
To have the greatest chance of crushing your oponents, Vayne players should equip the Lethal Tempo, Triumph, Legend: Alacrity, Coup de Grace, Conditioning, and Overgrowth runes from the Precision and Resolve rune sets. Out of all the runes players chose for Vayne and Seraphine pairings, this mixture of runes yielded the greatest win rate. Notably, these runes gave a 48.7% win rate overall.
By default, tips, statistics, and builds on how to synergize Seraphine with Vayne are shown for all skill levels combined. If you want to narrow the statistics and builds to a distinct rank, you can use the selection menu located earlier on the page.