Don't go in first to a large teamfight. Wait for your teammates to initiate.
Tumble has many uses, but it cannot pass over walls.
Condemn can be used to both pin targets to walls to ensure a kill, or to escape a pursuer.
Mortal Will activates after 5 spells or basic attacks - plan your way through fights to allow you to activate it more than once.
Whittle the enemy down with Comet Spears before you jump in.
If an enemy is going to get out of range of your Aegis Assault, you can recast the spell to immediately fire the shield slam.
The Vayne Pantheon synergy stats shown here demonstrate the areas of her gameplay that do better (or worse) when paired with Pantheon, compared to her overall stats. Significant differences are areas of focus that highlight how her gameplay changes when paired with this other champion.
Overall, Vayne sees a very large drop in her KDA (ratio of kills and assists to deaths) when paired with Pantheon. His KDA went down from NaN to NaN. This decrease shows that Pantheon helps Vayne perform worse in ranked LoL rounds. Yet, the small difference shows that this performance change is only marginal.
When Vayne is paired with Pantheon, she gets a little drop in her total damage output. This difference may signal that Pantheon does not support by providing protection for her to deal more damage or that his support also helps extend the game's duration. Similarly, when Vayne is played with Pantheon on the same side, he usually scores many fewer killing sprees compared to when she plays alone. This is contrasting evidence that she is worse when playing synergisticly with Pantheon.
Moreover, when Vayne plays with Pantheon on the same side, she typically takes a little less damage than when she fights alone. Taking not as much damage may mean that Pantheon does a decent job of covering Vayne during teamfights.
There is no top ally for Vayne that will 100% of the time be her ideal ally. However, Pantheon is a not very good companion for Vayne. By being on the same side as Vayne, he decreases their win rate by -1.5% to 48.8%. This clearly indicates that there is a negative synergy between Vayne and Pantheon that allows them to perform not as well together than alone.
Pantheon has a much lower diffuclty than Vayne. That means you don't need to be careful when lining up Pantheon teammates to fight alongside, as they will have to have a much lower level of skill to work well with you.
Fighting on the same side, Vayne players should expect to observe an overall large increase in your team’s ability to dish out massive AD. Combined, these two should be able to take down targets with auto-attacks and other AD damage abilities.
In contrast, by pairing Vayne and Pantheon together, you will not be providing your other teammates very much magical damage output. Plan to include other champions on your team that neutralizes this relative hole in this pairing's abilities.
Regardless of your Pantheon ally's skill level, you should focus on maximizing your income, warding to avoid ambushes, and clearing objectives. If you heed this simple advice, you will do well, regardless.
To truly master Vayne in order to work well with Pantheon during both the laning and mid / late game phases of League of Legends matches, you should keep reading to master some more tricks and insights into this champion pairing. If you listen to the build and suggestions presented here, you will grow your win rate significantly.
The most crucial finished items to build first in your Vayne and Pantheon synergy build include Guardian Angel, Wit's End, and Terminus. When Vayne used at least these three items in her build, she did a lot better when fighting alongside Pantheon than with most other commonly used builds. In fact, Vayne boasted an average win rate of 48.8% when playing alongside Pantheon with this build.
To have the greatest probability of crushing your oponents, Vayne players should take the Lethal Tempo, Triumph, Legend: Alacrity, Coup de Grace, Taste of Blood, and Treasure Hunter runes from the Precision and Domination rune sets. Of all the rune sets players used for this champion pairing, this combo of runes resulted in the greatest win rate. Notably, these runes gave a 48.8% win rate overall.
By default, tips, stats, and builds on how to team up Pantheon with Vayne are presented for all ranked divisions. If you want to filter the stats and builds to a specific skill level, you can use the selection menu located earlier in the counter matchup guide.