Don't go in first to a large teamfight. Wait for your teammates to initiate.
Tumble has many uses, but it cannot pass over walls.
Condemn can be used to both pin targets to walls to ensure a kill, or to escape a pursuer.
Use the CC from your abilities to land both of your Precision Protocol attacks on enemies.
Try waiting until the other team is distracted with fighting your team, and use Hookshot to pick off vulnerable targets.
The Vayne Camille synergy stats shown here demonstrate the areas of her gameplay that do better (or worse) when paired with Camille, compared to her overall stats. Significant differences are areas of focus that highlight how her gameplay changes when paired with this other champion.
Overall, Vayne sees a large worsening in her KDA (ratio of kills and assists to deaths) when paired with Camille. His KDA went down from NaN to NaN. This fall shows that Camille helps Vayne perform not as well in ranked LoL rounds. Yet, the small difference indicates that this performance change is not very impactful.
When Vayne is an ally to Camille, she sees a little drop in her full damage dealt. This could indicate that Camille doesn't help protection for her to deal more damage or that her support also helps increase the game's duration. Similarly, when Vayne is played together with Camille on the same team, he usually scores many fewer killing sprees compared to when she plays on his own. This is contrasting evidence that she is worse when playing with Camille.
Moreover, when Vayne plays with Camille on the same team, she often receives a little less damage than when she fights alone. Receiving not as much damage may indicate that Camille does a decent job of covering Vayne in team fights.
There is no one best champion pairing for Vayne that will 100% of the time be her #1 ally. Yet, Camille is a terrible teammate for Vayne. By playing on the same team as Vayne, she lowers their win rate by -3.9% to 46.4%. This proves that there is a terrible bond between Vayne and Camille that results in them performing worse together than without each other.
Camille has a much lower diffuclty than Vayne. That means Vayne players don't need to be careful when arranging Camille allies to fight alongside, as they will have to have a much lower level of skill to fight well with you.
Working together, Vayne players should expect to observe an overall large increase in your team’s capacity to deal physical damage. Combined, these two can provide a great amount of sustained physical damage.
Although, by pairing Vayne and Camille together, you probably will not be providing your other allies much magic damage. Make sure to pick other champs on your team that fills this gap in this pairing's capabilities.
Regardless of your Camille ally's skill level, you should focus on maximizing your gold income, outlasting your enemies, and taking down objectives. If you do this, you will do well, regardless.
If you would like to learn all of the intricacies of Vayne to work well with Camille during both the early game and mid / late game phases of League of Legends rounds, you should continue reading to learn a few extra tips and tricks for this champion pairing. If you pay attention to the build and stats shown above, you will grow your win rate significantly.
The best finished items to use in your Vayne and Camille synergy build include Wit's End, Guinsoo's Rageblade, and Kraken Slayer. When Vayne combined at least these three pieces in her build, she did significantly better when fighting alongside Camille than with many other typical builds. In fact, Vayne had an average winrate of 46.4% when playing alongside Camille with these items in her kit.
To have the highest chance of vanquishing your oponents, Vayne players should equip the Lethal Tempo, Triumph, Legend: Alacrity, Coup de Grace, Conditioning, and Overgrowth runes from the Precision and Resolve rune sets. Out of all the rune combinations players used for Vayne and Camille pairings, this blending of runes yielded the top win rate. Notably, these runes provided a 46.4% winrate overall.
If you would like to see Vayne and Camille synergy tips and builds for a a particular division rank, feel free to select one from the selection menu displayed above. If viewing for the first time, the stats and strategies given are computed using all rounds run with both champions.