Contaminate has a large range; apply as many stacks of Deadly Venom as possible before using it.
You can catch up to an enemy out of attack range with Venom Cask.
Twitch's Attack Speed is among the highest in the game; try purchasing items with on-hit effects such as Black Cleaver or Wit's End.
Be very careful about when to use Life Form Disintegration Ray. Many champions have abilities that can interrupt the spell.
Shooting Plasma Fission diagonally and splitting at maximum range allows you to hit opponents that are out of the range of the initial missile, but is more challenging to pull off.
When laning, use Void Rift to kill minions while building stacks of Organic Deconstruction on your opponent. You can then follow up with your other abilities.
The Twitch Vel'Koz synergy stats shown here demonstrate the areas of his gameplay that do better (or worse) when paired with Vel'Koz, compared to his overall stats. Significant differences are areas of focus that highlight how his gameplay changes when paired with this other champion.
Overall, Twitch sees a large worsening in his KDA (ratio of kills and assists to deaths) when paired with Vel'Koz. His KDA decreased from NaN to NaN. This decrease shows that Vel'Koz helps Twitch perform worse in competitive League games. Yet, the small difference shows that this performance change is only marginal.
When Twitch is an ally to Vel'Koz, he gets a barely noticable drop in his complete damage dealt. This could signal that Vel'Koz does not provide cover for him to dish out more damage or that his presence also helps increase the match's duration. Similarly, when Twitch is played with Vel'Koz on the same side, he usually scores many fewer killing sprees than when he plays on his own. This is contrasting evidence that he is worse when playing synergisticly with Vel'Koz.
Moreover, when Twitch plays with Vel'Koz on the same side, he often receives a little more damage than when he fights alone. Taking more damage may mean that Vel'Koz does a poor job of covering Twitch during teamfights.
There is no perfect champion pairing for Twitch that will no matter what be his top teammate. However, Vel'Koz is a very typical ally for Twitch. By locking into the same team as Twitch, he improves their win rate by 0.1% to 50.1%. This proves that there is a weak bond between Twitch and Vel'Koz that results in them performing at the top of their game together than without each other.
Vel'Koz has a greater difficulty than Twitch. That means you should be careful when arranging Vel'Koz teammates to fight alongside, as they will have to have a greater level of skill to fight well with you.
Fighting alongside, Twitch players should expect to see an overall large increase in your team’s ability to to do a lot of AP damage. Combined, these champions are able to dish out a surprising amount of magic type damage.
Although, by pairing Twitch and Vel'Koz together, you may not be giving your team enough engage potential. We recommend you have other champs on your team that nullifies this relative hole in their abilities.
Regardless of the skill of your Vel'Koz teammate, you should focus on maximizing your income, warding to avoid ambushes, and taking down objectives. If you do this, you will do well, regardless.
To truly master Twitch in order to pair well with Vel'Koz during both the laning and mid / late game phases of League, you should continue reading to learn additional tricks and insights into this champion pairing. If you listen to the build and stats presented here, you will grow your win rate significantly.
The ideal items to use in your Twitch and Vel'Koz synergy build include Runaan's Hurricane, Terminus, and Kraken Slayer. When Twitch incorporated at least these three items in his build, he performed a lot better as an ally of Vel'Koz than with many other common builds. In fact, Twitch boasted an average win rate of 50.1% when playing alongside Vel'Koz with this build.
To have the highest probability of vanquishing your oponents, you should take the Lethal Tempo, Presence of Mind, Legend: Alacrity, Coup de Grace, Taste of Blood, and Treasure Hunter runes from the Precision and Domination rune sets. Of all the rune builds players chose for this champion pairing, this set of runes yielded the greatest win rate. Notably, these runes averaged a 50.1% win rate overall.
By default, tips, stats, and builds on how to synergize Vel'Koz with Twitch are given for all skill levels combined. If you would like to scope the stats and builds to a particular player tier, you should use the selection menu earlier on the page.