Contaminate has a large range; apply as many stacks of Deadly Venom as possible before using it.
You can catch up to an enemy out of attack range with Venom Cask.
Twitch's Attack Speed is among the highest in the game; try purchasing items with on-hit effects such as Black Cleaver or Wit's End.
Shadow Assault is a powerful escape tool, but can also be offensively used to assault a group.
You can use Assassin's Path to get behind the enemy and set up for Noxian Diplomacy's melee attack.
Remember to pick your target before the fight. Focusing all of Talon's abilities on one target can be very rewarding, but splitting them up between many may leave you helpless.
The Twitch Talon synergy stats shown here demonstrate the areas of his gameplay that do better (or worse) when paired with Talon, compared to his overall stats. Significant differences are areas of focus that highlight how his gameplay changes when paired with this other champion.
Overall, Twitch sees a large worsening in his KDA (ratio of kills and assists to deaths) when paired with Talon. His KDA fell from NaN to NaN. This negative change shows that Talon helps Twitch perform worse in ranked League of Legends games. Yet, the small difference demonstrates that this performance change is not very impactful.
When Twitch plays on the same team as Talon, he gets a small increase in his complete damage output. This difference could signal that Talon helps provide protection for him to dish out more damage or that his allyship also helps increase the game's duration. Similarly, when Twitch is played with Talon on the same side, he usually scores many fewer killing sprees compared to when he plays without Talon. This is contrasting evidence that he is worse when playing synergisticly with Talon.
Additionally, when Twitch plays with Talon on the same team, he on average receives a little more damage than when he fights alone. Taking more damage may mean that Talon does a poor job of protecting Twitch during team fights.
There is no top synergy for Twitch that will always be his #1 synergy. However, Talon is a very typical ally for Twitch. By being on the same team as Twitch, he drops their win rate by -0.6% to 49.4%. This clearly indicates that there is a weak bond between Twitch and Talon that allows them to perform not as well together than without each other.
Talon has a greater difficulty than Twitch. That means you need to be careful when arranging Talon allies to play with, as they will require a greater level of skill to be able to play well with you.
Fighting cooperatively, you will likely observe an overall large increase in your team’s capability to destroy wih physical damage. When paired, these champs can tear through the other team with a lot of physcial damage.
Conversely, by bringing Twitch and Talon together, you may not be granting your other teammates enough magic damage. Make sure to pick other champs on your team that neutralizes this disparity in this pairing's kit.
Regardless of the ability of your Talon ally, you should focus on increasing your income, warding to avoid ambushes, and clearing objectives. If you heed this simple advice, you should do well, regardless.
If you would like to truly master Twitch in order to work well with Talon during both the lane and mid / late game phases of League rounds, you should keep reading to gather some more tips and tricks for this champion pairing. If you mind the build and tips displayed above, you will grow your win rate significantly.
The ideal items to include in your Twitch and Talon synergy build include Experimental Hexplate, Runaan's Hurricane, and Blade of The Ruined King. When Twitch used at least these three great items in his build, he did a lot better when paired up with Talon than with many other commonly used builds. In fact, Twitch boasted an average winrate of 49.4% helping carry Talon with these items in his kit.
To have the greatest probability of coming out on top against your oponents, you should equip the Lethal Tempo, Presence of Mind, Legend: Alacrity, Coup de Grace, Biscuit Delivery, and Magical Footwear runes from the Precision and Inspiration rune sets. Of all the runes players picked for Twitch and Talon pairings, this composite of runes resulted in the greatest win rate. In fact, these runes averaged a 49.4% win rate overall.
By default, tips, stats, and builds on how to synergize Talon with Twitch are displayed for all skill levels combined. If you would like to filter the stats and builds to a particular player tier, you should use the selection menu located earlier in the counter matchup guide.