Contaminate has a large range; apply as many stacks of Deadly Venom as possible before using it.
You can catch up to an enemy out of attack range with Venom Cask.
Twitch's Attack Speed is among the highest in the game; try purchasing items with on-hit effects such as Black Cleaver or Wit's End.
The Twitch Sett synergy stats shown here demonstrate the areas of his gameplay that do better (or worse) when paired with Sett, compared to his overall stats. Significant differences are areas of focus that highlight how his gameplay changes when paired with this other champion.
Overall, Twitch sees a large worsening in his KDA (ratio of kills and assists to deaths) when paired with Sett. His KDA decreased from NaN to NaN. This fall shows that Sett helps Twitch perform poorer in ranked League of Legends matches. Yet, the small difference demonstrates that this performance change is only marginal.
When Twitch tries to synergize with Sett, he gets a little decrease in his complete damage dealt. This change could indicate that Sett does not provide cover for him to dish out more damage or that his participation also helps increase the match's duration. Similarly, when Twitch is played with Sett on the same team, he usually scores many fewer killing sprees compared to when he plays on his own. This is contrasting evidence that he is worse when playing alongside Sett.
Moreover, when Twitch plays with Sett on the same side, he on average receives a little more damage than when he plays alone. Taking more damage may indicate that Sett does a poor job of covering Twitch during team fights.
There is no ideal champion pairing for Twitch that will 100% of the time be his #1 ally. However, overall, Sett is a very typical ally for Twitch. By playing on the same team as Twitch, he improves their win rate by 0.4% to 50.4%. This signals that there is a weak bond between Twitch and Sett that results in them performing stronger together than without each other.
Sett has a much lower diffuclty than Twitch. That means you don't need to be very careful when lining up Sett comrades to go into battle on the same side as, as they will need a much lower level of skill to be able to fight well with you.
When playing on the same side, Twitch players will likely witness an overall large increase in your team’s capability to deal physical damage. Together, these champions can tear through the other team with a lot of physcial damage.
Conversely, by pairing Twitch and Sett together, you may not be granting your other allies enough AP. Make sure to pick other champions on your team that neutralizes this disparity in their abilities.
Regardless of your Sett ally's ability, you should focus on increasing your gold income, warding to avoid ambushes, and clearing objectives. If you follow these simple suggestions, you will do well, regardless.
To learn all of the intricacies of Twitch in order to synergize with Sett during both the laning and mid / late game phases of League rounds, you should keep reading to master some more tricks and insights into this champion pairing. If you use the build and stats shown above, you should grow your win rate by a lot.
The best items to have in your Twitch and Sett synergy build consist of Rabadon's Deathcap, Banshee's Veil, and Nashor's Tooth. When Twitch used at least these three pieces in his build, he did much better when paired up with Sett than with most other typical item sets. In fact, Twitch had an average winrate of 50.4% when playing alongside Sett with this build.
To have the highest likelihood of annihilating your oponents, you should equip the Lethal Tempo, Presence of Mind, Legend: Alacrity, Coup de Grace, Biscuit Delivery, and Magical Footwear runes from the Precision and Inspiration rune sets. Out of all the rune builds that we analyzed for Twitch and Sett pairings, this order of runes resulted in the greatest win rate. In fact, these runes averaged a 50.4% win rate overall.
By default, tips, statistics, and builds on how to synergize Sett with Twitch are shown for every ranked division. If you would like to narrow the statistics and builds to a particular skill level, you can use the selection menu earlier on the page.