Contaminate has a large range; apply as many stacks of Deadly Venom as possible before using it.
You can catch up to an enemy out of attack range with Venom Cask.
Twitch's Attack Speed is among the highest in the game; try purchasing items with on-hit effects such as Black Cleaver or Wit's End.
Paying attention to last hitting with Siphoning Strike will have a large impact at the end of a game.
If you're solo, Spirit Fire is a great way to farm a lane. It can be bad if you're in a lane with 2 and you push too far. Find the right balance between Siphoning Strike last hits and AoE farming.
If you have low defenses, people will focus you down even during your ultimate. Try buying some survivability items even in your DPS builds.
The Twitch Nasus synergy stats shown here demonstrate the areas of his gameplay that do better (or worse) when paired with Nasus, compared to his overall stats. Significant differences are areas of focus that highlight how his gameplay changes when paired with this other champion.
Overall, Twitch sees a very large drop in his KDA (ratio of kills and assists to deaths) when paired with Nasus. His KDA worsened from NaN to NaN. This fall shows that Nasus helps Twitch perform not as well in competitive League of Legends rounds. Yet, the small difference demonstrates that this performance change is not very impactful.
When Twitch plays on the same team as Nasus, he sees a barely noticable drop in his total damage output. This may demonstrate that Nasus does not provide cover for him to dish out more damage or that his presence on the team also helps increase the round's duration. Similarly, when Twitch is played with Nasus on the same side, he usually scores many fewer killing sprees than when he plays alone. This is contrasting evidence that he is worse when playing with Nasus.
Moreover, when Twitch plays with Nasus on the same side, he usually takes a little less damage than when he fights alone. Taking not as much damage could indicate that Nasus does a decent job of protecting Twitch during team fights.
There is no perfect synergy for Twitch that will 100% of the time be his #1 synergy. However, overall, Nasus is a very typical companion for Twitch. By locking into the same team as Twitch, he increases their win rate by 0.5% to 50.5%. This shows that there is only a small bond between Twitch and Nasus that results in them performing at the top of their game together than alone.
Nasus has a lower difficulty than Twitch. That means Twitch players don't need to be careful when lining up Nasus comrades to play with, as they will require a lower level of skill to play well with you.
Fighting alongside, you will likely witness an overall large increase in your team’s capacity to deal physical damage. When paired, these champions can provide a great amount of sustained physical damage.
Conversely, by aligning Twitch and Nasus together, you will not be granting your other teammates very much crowd control. Make sure to have other champions on your team that offsets this hole in this pairing's capabilities.
Regardless of the skill of your Nasus teammate, you should focus on maximizing your gold income, outlasting your enemies, and clearing objectives. If you follow these simple suggestions, you will do well, regardless.
To truly master Twitch to work well with Nasus during both the lane and mid / late game phases of LoL, you should continue reading to master additional tricks and insights into this champion pairing. If you pay attention to the build and suggestions shown here, you will grow your win rate significantly.
The most important finished items to focus on in your Twitch and Nasus synergy build consist of Wit's End, Blade of The Ruined King, and Terminus. When Twitch bought at least these three great items in his build, he performed a lot better as an ally of Nasus than with many other commonly used item sets. In fact, Twitch boasted an average winrate of 50.5% when synergizing his build and playstyle to Nasus with these items in his kit.
To have the greatest likelihood of beating your oponents, you should take the Lethal Tempo, Presence of Mind, Legend: Alacrity, Coup de Grace, Biscuit Delivery, and Magical Footwear runes from the Precision and Inspiration rune sets. Out of all the runes that we analyzed for Twitch and Nasus pairings, this blending of runes yielded the highest win rate. Moreover, these runes averaged a 50.5% winrate overall.
By default, tips, statistics, and builds on how to pair Nasus with Twitch are shown for all ranked divisions. If you would like to narrow the stats and builds to an individual division, you may use the selection menu located earlier on the page.