Contaminate has a large range; apply as many stacks of Deadly Venom as possible before using it.
You can catch up to an enemy out of attack range with Venom Cask.
Twitch's Attack Speed is among the highest in the game; try purchasing items with on-hit effects such as Black Cleaver or Wit's End.
If you have trouble landing Prismatic Barrier, remember that it returns to you after it reaches max range. Try positioning yourself to hit your allies with its return trip.
Lux has great zone control abilities. Try to set up Lucent Singularity to prevent an enemy's advance or escape.
Lucent Singularity is a great scouting tool. Try throwing it into brush before walking into it to check for ambushes.
The Twitch Lux synergy stats shown here demonstrate the areas of his gameplay that do better (or worse) when paired with Lux, compared to his overall stats. Significant differences are areas of focus that highlight how his gameplay changes when paired with this other champion.
Overall, Twitch sees a large worsening in his KDA (ratio of kills and assists to deaths) when paired with Lux. His KDA decreased from NaN to NaN. This negative change shows that Lux helps Twitch perform not as well in ranked League rounds. Yet, the small difference demonstrates that this performance change is only marginal.
When Twitch plays on the same team as Lux, he sees a little decrease in his full damage output. This could signal that Lux does not help cover for him to deal more damage or that her presence on the team also helps increase the round's duration. Similarly, when Twitch is played alongside Lux on the same team, he usually scores many fewer killing sprees compared to when he plays without Lux. This is contrasting evidence that he is worse when playing synergisticly with Lux.
Moreover, when Twitch plays with Lux on the same team, he usually takes a little more damage than when he plays alone. Receiving more damage could mean that Lux does a poor job of protecting Twitch in teamfights.
There is no one best companion for Twitch that will always be his #1 teammate. However, overall, Lux is a below average ally for Twitch. By playing on the same team as Twitch, she lowers their win rate by -1.6% to 48.4%. This clearly indicates that there is a harmful bond between Twitch and Lux that results in them performing worse together than without each other.
Lux has a lower difficulty than Twitch. That means Twitch players don't need to be cautious when lining up Lux comrades to go into battle on the same side as, as they will require a lower level of skill to be able to cooperate well with you.
Fighting alongside, Twitch players will likely see an overall large increase in your team’s capability to deal magical damage. Together, these champions can blast through enemies with magic damage.
In contrast, by bringing Twitch and Lux together, you may not be granting your other allies very much cover. Plan to bring other champions on your team that offsets this hole in their capabilities.
Regardless of the ability of your Lux teammate, you should focus on maximizing your gold income, outlasting your enemies, and clearing objectives. If you heed this simple advice, you will do well anyway.
To truly master Twitch to work well with Lux during both the laning and mid / late game phases of League of Legends matches, you should keep reading to pick up a few extra tricks and insights into this champion pairing. If you mind the build and tips presented here, you should increase your win rate by a lot.
The most important items to include in your Twitch and Lux synergy build consist of Wit's End, Guinsoo's Rageblade, and Terminus. When Twitch included at least these three pieces in his build, he did significantly better as an ally of Lux than with most other common item sets. In fact, Twitch had an average winrate of 48.4% helping carry Lux with these items in his kit.
To have the best likelihood of coming out on top against your oponents, Twitch players should take the Hail of Blades, Taste of Blood, Eyeball Collection, Relentless Hunter, Legend: Alacrity, and Presence of Mind runes from the Domination and Precision rune sets. Out of all the rune combinations players used for this champion pairing, this mix of runes resulted in the greatest win rate. Notably, these runes provided a 48.4% win rate overall.
By default, tips, stats, and builds on how to team up Lux with Twitch are shown for all ranked divisions. If you want to scope the statistics and builds to an individual player tier, you should use the selection menu located earlier on the page.