Contaminate has a large range; apply as many stacks of Deadly Venom as possible before using it.
You can catch up to an enemy out of attack range with Venom Cask.
Twitch's Attack Speed is among the highest in the game; try purchasing items with on-hit effects such as Black Cleaver or Wit's End.
The Twitch Lillia synergy stats shown here demonstrate the areas of his gameplay that do better (or worse) when paired with Lillia, compared to his overall stats. Significant differences are areas of focus that highlight how his gameplay changes when paired with this other champion.
Overall, Twitch sees a large worsening in his KDA (ratio of kills and assists to deaths) when paired with Lillia. His KDA fell from NaN to NaN. This drop shows that Lillia helps Twitch perform not as well in ranked League rounds. Yet, the small difference shows that this performance change is not very impactful.
When Twitch is an ally to Lillia, he gets a barely noticable drop in his complete damage output. This change could indicate that Lillia does not help protection for him to dish out more damage or that her participation also helps increase the game's duration. Similarly, when Twitch is played alongside Lillia on the same side, he usually scores many fewer killing sprees than when he plays on his own. This is contrasting evidence that he is worse when playing alongside Lillia.
Additionally, when Twitch plays with Lillia on the same side, he on average receives a little less damage than when he fights alone. Receiving not as much damage could indicate that Lillia does a decent job of protecting Twitch in team fights.
There is no top ally for Twitch that will no matter what be his #1 synergy. However, overall, Lillia is a top-tier companion for Twitch. By being on the same side as Twitch, she increases their win rate by 4.4% to 54.4%. This clearly indicates that there is a strong synergy between Twitch and Lillia that results in them performing at the top of their game together than without each other.
Lillia has a greater difficulty than Twitch. That means Twitch players should be very careful when arranging Lillia allies to play with, as they will require a greater level of skill to be able to cooperate well with you.
Playing cooperatively, you should expect to see an overall large increase in your team’s capacity to deal magic damage. Combined, these champions can deal quite a lot of AP type damage.
Although, by bringing Twitch and Lillia together, you probably will not be granting your other allies a lot of tankyness. Make sure to include other champions on your team that neutralizes this disparity in this pairing's playstyle.
Regardless of your Lillia ally's skill level, you need to focus on maximizing your gold income, warding to avoid ambushes, and taking down objectives. If you heed this simple advice, you will do well anyway.
If you would like to learn all of the intricacies of Twitch in order to synergize with Lillia during both the early game and mid / late game phases of League of Legends rounds, you should continue reading to pick up some more tricks and insights into this champion pairing. If you use the build and tips presented here, you should increase your win rate significantly.
The top finished items to build first in your Twitch and Lillia synergy build include Infinity Edge, Bloodthirster, and Runaan's Hurricane. When Twitch included at least these three pieces in his build, he did a lot better when fighting alongside Lillia than with many other common item sets. In fact, Twitch had an average win rate of 54.4% when playing alongside Lillia with these items in his kit.
To have the highest likelihood of vanquishing your oponents, Twitch players should take the Hail of Blades, Taste of Blood, Eyeball Collection, Relentless Hunter, Presence of Mind, and Legend: Alacrity runes from the Domination and Precision rune sets. Of all the rune sets players picked for Twitch and Lillia pairings, this mixture of runes resulted in the best win rate. In fact, these runes gave a 54.4% win rate overall.
By default, tips, stats, and builds on how to team up Lillia with Twitch are presented for all skill levels, merged. To filter the statistics and builds to a distinct rank, you should use the selection menu earlier on the page.