Communication is key when making use of Thresh's lantern. Let your teammates know how you like to use it.
Death Sentence and Flay can be combined in either cast order for powerful combinations.
Thresh can collect souls without needing to kill units himself. Planning your map position to be near the most deaths will help to maximize soul collection.
Don't go in first to a large teamfight. Wait for your teammates to initiate.
Tumble has many uses, but it cannot pass over walls.
Condemn can be used to both pin targets to walls to ensure a kill, or to escape a pursuer.
The Thresh Vayne synergy stats shown here demonstrate the areas of his gameplay that do better (or worse) when paired with Vayne, compared to his overall stats. Significant differences are areas of focus that highlight how his gameplay changes when paired with this other champion.
Overall, Thresh sees a very large drop in his KDA (ratio of kills and assists to deaths) when paired with Vayne. His KDA worsened from NaN to NaN. This drop shows that Vayne helps Thresh perform worse in ranked LoL games. Yet, the small difference shows that this performance change is only marginal.
When Thresh tries to synergize with Vayne, he sees a little decrease in his total damage output. This difference could demonstrate that Vayne does not provide protection for him to deal more damage or that her presence also helps increase the round's duration. Similarly, when Thresh is played alongside Vayne on the same side, he usually scores many fewer killing sprees than when he plays alone. This is contrasting evidence that he is worse when playing with Vayne.
Moreover, when Thresh plays with Vayne on the same team, he often receives a little less damage than when he fights alone. Getting dealt not as much damage may indicate that Vayne does a decent job of protecting Thresh during teamfights.
There is no one best companion for Thresh that will always be his #1 teammate. However, overall, Vayne is a very typical teammate for Thresh. By playing on the same team as Thresh, she increases their win rate by 0.1% to 48.6%. This demonstrates that there is only a small synergy between Thresh and Vayne that allows them to perform stronger together than alone.
Vayne has a greater difficulty than Thresh. That means Thresh players should be very careful when finding Vayne comrades to go into battle on the same side as, as they will have to have a greater level of skill to be able to cooperate well with you.
Working cooperatively, Thresh players will likely witness an overall large increase in your team’s capacity to deal physical damage. Together, these two should be able to take down targets with auto-attacks and other AD damage abilities.
Conversely, by grouping Thresh and Vayne together, you will not be providing your other teammates very much AP. Plan to have other champs on your team that helps cover this gap in this pairing's kit.
Regardless of your Vayne ally's skill level, you need to focus on maximizing your income, warding to avoid ambushes, and clearing objectives. If you do this, you will do well, regardless.
If you would like to truly master Thresh in order to pair well with Vayne during both the early game and mid / late game phases of League of Legends games, you should continue reading to learn a few extra lessons on this champion pairing. If you pay attention to the build and suggestions shown here, you should grow your win rate by a lot.
The best items to have in your Thresh and Vayne synergy build consist of Knight's Vow, Frozen Heart, and Locket of the Iron Solari. When Thresh used at least these three finished items in his build, he performed much better as an ally of Vayne than with most other commonly used item sets. In fact, Thresh had an average win rate of 48.6% helping carry Vayne with this build.
To have the best probability of beating your oponents, you should take the Guardian, Font of Life, Bone Plating, Unflinching, Biscuit Delivery, and Cosmic Insight runes from the Resolve and Inspiration rune sets. Out of all the rune sets that we analyzed for Thresh and Vayne pairings, this set of runes yielded the best win rate. Notably, these runes averaged a 48.6% win rate overall.
By default, tips, statistics, and builds on how to pair Vayne with Thresh are presented for all skill levels combined. If you would like to narrow the stats and builds to a particular player tier, you may use the selection menu located earlier in the counter matchup guide.