Teemo's mushrooms can be used to farm creep waves very effectively.
Place your mushrooms at key locations on the map, such as by the Dragon or Baron Nashor, to reveal when your enemies might be attempting to kill them.
Make sure to buy items that will evolve at least 1 or 2 of your spells.
Work with your teammates to set up your Ultimate and optimize damage with your passive.
Try to catch enemy carries alone to burst them with Icathian Rain.
The Teemo Kai'Sa synergy stats shown here demonstrate the areas of his gameplay that do better (or worse) when paired with Kai'Sa, compared to his overall stats. Significant differences are areas of focus that highlight how his gameplay changes when paired with this other champion.
Overall, Teemo sees a large worsening in his KDA (ratio of kills and assists to deaths) when paired with Kai'Sa. His KDA decreased from NaN to NaN. This fall shows that Kai'Sa helps Teemo perform not as well in competitive LoL games. Yet, the small difference demonstrates that this performance change is only marginal.
When Teemo plays on the same team as Kai'Sa, he gets a little increase in his total damage dealt. This difference may demonstrate that Kai'Sa provides protection for him to dish out more damage or that her presence on the team also helps extend the round's duration. Similarly, when Teemo is played alongside Kai'Sa on the same side, he usually scores many fewer killing sprees than when he plays on his own. This is contrasting evidence that he is worse when playing alongside Kai'Sa.
Additionally, when Teemo plays with Kai'Sa on the same side, he on average receives a little more damage than when he plays alone. Receiving more damage may mean that Kai'Sa does a poor job of protecting Teemo during team fights.
There is no one best synergy for Teemo that will 100% of the time be his top ally. Yet, Kai'Sa is a terrible ally for Teemo. By locking into the same side as Teemo, she lowers their win rate by -4.4% to 48.2%. This proves that there is an easy to overcome and exploit synergy between Teemo and Kai'Sa that results in them performing worse together than alone.
Kai'Sa has a lower difficulty than Teemo. That means Teemo players don't need to be very careful when lining up Kai'Sa allies to play with, as they will have to have a relatively low level of skill to work well with you.
Working on the same side, you should see an overall large increase in your team’s capacity to deal physical damage. Together, these champs can provide a great amount of sustained physical damage.
Although, by bringing Teemo and Kai'Sa together, you will not be granting your team very much utility. Plan to pick other champs on your team that nullifies this relative gap in their abilities.
Regardless of your Kai'Sa ally's ability, you should focus on increasing your income, outlasting your enemies, and clearing objectives. If you heed this simple advice, you will do well anyway.
To learn all of the intricacies of Teemo to pair well with Kai'Sa during both the laning and mid / late game phases of League rounds, you should keep reading to gather additional tips and tricks for this champion pairing. If you mind the build and suggestions presented above, you should increase your win rate significantly.
The most important items to use in your Teemo and Kai'Sa synergy build include Rabadon's Deathcap, Malignance, and Shadowflame. When Teemo incorporated at least these three items in his build, he performed much better when fighting alongside Kai'Sa than with most other common item sets. In fact, Teemo boasted an average winrate of 48.2% helping carry Kai'Sa with this build.
To have the greatest probability of annihilating your oponents, Teemo players should use the Dark Harvest, Cheap Shot, Eyeball Collection, Ultimate Hunter, Gathering Storm, and Transcendence runes from the Domination and Sorcery rune sets. Of all the runes players picked for this team composition, this mixture of runes resulted in the highest win rate. Notably, these runes gave a 48.2% winrate overall.
If you want to get Teemo and Kai'Sa synergy tips and builds for a a distinct skill level, feel free to choose one from the selection menu shown above. By default, the statistics and strategies shown are calculated using all rounds played with these champions.