Lay Waste is very strong at farming minions and harassing enemy champions.
Ask your allies to help point out when you should use Requiem to get kills in different lanes.
The Sett Karthus synergy stats shown here demonstrate the areas of his gameplay that do better (or worse) when paired with Karthus, compared to his overall stats. Significant differences are areas of focus that highlight how his gameplay changes when paired with this other champion.
Overall, Sett sees a large worsening in his KDA (ratio of kills and assists to deaths) when paired with Karthus. His KDA fell from NaN to NaN. This decrease shows that Karthus helps Sett perform worse in competitive LoL games. Yet, the small difference demonstrates that this performance change is not very impactful.
When Sett is an ally to Karthus, he sees a small increase in his complete damage dealt. This may demonstrate that Karthus provides cover for him to dish out more damage or that his allyship also helps increase the round's duration. Similarly, when Sett is played together with Karthus on the same side, he usually scores many fewer killing sprees than when he plays on his own. This is contrasting evidence that he is worse when playing alongside Karthus.
Additionally, when Sett plays with Karthus on the same side, he often receives more damage than when he plays alone. Taking more damage could indicate that Karthus does a poor job of covering Sett during teamfights.
There is no universally accepted best companion for Sett that will always be his #1 ally. Yet, overall, Karthus is a below average companion for Sett. By locking into the same side as Sett, he lowers their win rate by -1.2% to 49.3%. This proves that there is a bad bond between Sett and Karthus that allows them to perform worse together than alone.
Karthus has a much greater difficulty compared to Sett. That means Sett players should be cautious when finding Karthus allies to go into battle on the same side as, as they will have to have a much higher level of skill to work well with you.
Working on the same side, Sett players should expect to witness an overall large increase in your team’s ability to to do a lot of AP damage. When paired, these champs can deal quite a lot of AP type damage.
Conversely, by bringing Sett and Karthus together, you may not be giving your side much utility. Plan to have other champions on your team that fills this gap in this pairing's abilities.
Regardless of your Karthus ally's ability, you should focus on maximizing your gold income, outlasting your enemies, and clearing objectives. If you do this, you will do well anyway.
To learn all of the intricacies of Sett in order to synergize with Karthus during both the laning and mid / late game phases of League of Legends matches, you should keep reading to pick up additional lessons on this champion pairing. If you pay attention to the build and stats displayed here, you will grow your win rate by a lot.
The most crucial items to prioritize in your Sett and Karthus synergy build include Sterak's Gage, Sundered Sky, and Stridebreaker. When Sett incorporated at least these three finished items in his build, he did much better when paired up with Karthus than with many other commonly used item sets. In fact, Sett boasted an average win rate of 49.3% when playing alongside Karthus with these items in his kit.
To have the best chance of defeating your oponents, Sett players should take the Lethal Tempo, Triumph, Legend: Alacrity, Last Stand, Second Wind, and Unflinching runes from the Precision and Resolve rune sets. Of all the rune sets that we analyzed for Sett and Karthus pairings, this combination of runes yielded the greatest win rate. Notably, these runes averaged a 49.3% winrate overall.
If you need to view Sett with Karthus collaboration tips and stats for a a particular player tier, please choose one from the selection menu displayed above. At first, the statistics and tips and suggestions shown are calculated using all rounds with data with these champs.