You can set her passive to use hotkeys in the options menu. The default is Shift+F1~F5
Try to use Inherent Glamour sparingly, ineffective uses will put enemies on the alert.
The Senna Neeko synergy stats shown here demonstrate the areas of her gameplay that do better (or worse) when paired with Neeko, compared to her overall stats. Significant differences are areas of focus that highlight how her gameplay changes when paired with this other champion.
Overall, Senna sees a large worsening in her KDA (ratio of kills and assists to deaths) when paired with Neeko. His KDA fell from NaN to NaN. This decrease shows that Neeko helps Senna perform worse in ranked League games. Yet, the small difference indicates that this performance change is not very impactful.
When Senna tries to synergize with Neeko, she gets a little increase in her full damage dealt. This difference could indicate that Neeko helps provide cover for her to dish out more damage or that her support also helps increase the match's duration. Similarly, when Senna is played alongside Neeko on the same side, he usually scores many fewer killing sprees compared to when she plays alone. This is contrasting evidence that she is worse when playing synergisticly with Neeko.
Moreover, when Senna plays with Neeko on the same team, she often takes a little more damage than when she fights alone. Receiving more damage may mean that Neeko does a poor job of protecting Senna in teamfights.
There is no top champion pairing for Senna that will 100% of the time be her #1 synergy. However, Neeko is a very typical companion for Senna. By locking into the same team as Senna, she improves their win rate by 0.4% to 51.2%. This proves that there is a weak bond between Senna and Neeko that results in them performing better together than without each other.
Neeko has a lower difficulty than Senna. That means you don't need to be very careful when arranging Neeko comrades to go into battle on the same side as, as they will require a lower level of skill to be able to play well with you.
Fighting on the same side, you should expect to observe an overall large increase in your team’s capability to to do a lot of AP damage. When paired, these champions can blast through enemies with magic damage.
In contrast, by bringing Senna and Neeko together, you probably will not be granting your other teammates a great deal of engage. Plan to pick other champs on your team that nullifies this gap in this pairing's kit.
Regardless of the skill of your Neeko ally, you should focus on increasing your income, outlasting your enemies, and clearing objectives. If you do this, you should do well anyway.
If you would like to learn all of the intricacies of Senna to work well with Neeko during both the lane and mid / late game phases of League rounds, you should keep reading to pick up some more lessons on this champion pairing. If you pay attention to the build and suggestions displayed above, you will increase your win rate significantly.
The best finished items to have in your Senna and Neeko synergy build consist of Youmuu's Ghostblade, Edge of Night, and Bloodsong. When Senna incorporated at least these three great items in her build, she did significantly better as an ally of Neeko than with most other typical item sets. In fact, Senna had an average winrate of 51.2% helping carry Neeko with this build.
To have the highest probability of coming out on top against your oponents, Senna players should use the Fleet Footwork, Presence of Mind, Legend: Alacrity, Cut Down, Bone Plating, and Revitalize runes from the Precision and Resolve rune sets. Of all the runes players chose for this champion pairing, this combo of runes yielded the top win rate. Moreover, these runes averaged a 51.2% winrate overall.
If you want to see Senna and Neeko collaboration tips and stats for a a specific division, feel free to choose one from the selection menu displayed above. At first, the statistics and build suggestions displayed are computed using all matches completed with both champs.