Take advantage of Flurry by weaving in basic attacks between spell casts - this maximizes damage output and minimizes Energy loss.
Self-casting Safeguard and using Iron Will are powerful tools for killing neutral monsters (in the jungle).
Use Sonic Wave before Dragon's Rage so you can chase the target with Resonating Strike.
The Senna Lee Sin synergy stats shown here demonstrate the areas of her gameplay that do better (or worse) when paired with Lee Sin, compared to her overall stats. Significant differences are areas of focus that highlight how her gameplay changes when paired with this other champion.
Overall, Senna sees a large worsening in her KDA (ratio of kills and assists to deaths) when paired with Lee Sin. His KDA went down from NaN to NaN. This worsening shows that Lee Sin helps Senna perform poorer in ranked League of Legends games. Yet, the small difference proves that this performance change is not very impactful.
When Senna is paired with Lee Sin, she gets a barely noticable drop in her complete damage dealt. This may signal that Lee Sin does not support by providing cover for her to dish out more damage or that his support also helps increase the match's duration. Similarly, when Senna is played with Lee Sin on the same team, he usually scores many fewer killing sprees compared to when she plays on his own. This is contrasting evidence that she is worse when playing synergisticly with Lee Sin.
Moreover, when Senna plays with Lee Sin on the same side, she typically takes a little less damage than when she fights alone. Taking not as much damage could mean that Lee Sin does a decent job of covering Senna in teamfights.
There is no universally accepted best companion for Senna that will no matter what be her top ally. However, overall, Lee Sin is a below average ally for Senna. By locking into the same side as Senna, he lowers their win rate by -2.7% to 48.1%. This shows that there is a bad synergy between Senna and Lee Sin that allows them to perform worse together than without each other.
Lee Sin has a lower difficulty than Senna. That means Senna players don't need to be very careful when finding Lee Sin teammates to fight alongside, as they will need a lower level of skill to do well with you.
Working together, Senna players should expect to observe an overall large increase in your team’s capacity to destroy wih physical damage. Together, these champs can provide a great amount of sustained physical damage.
In contrast, by pairing Senna and Lee Sin together, you probably will not be providing your side much engage potential. Make sure to have other champions on your team that helps cover this hole in this pairing's playstyle.
Regardless of your Lee Sin ally's ability, you should focus on increasing your income, warding to avoid ambushes, and clearing objectives. If you follow these simple suggestions, you will do well anyway.
If you would like to truly master Senna in order to work well with Lee Sin during both the early game and mid / late game phases of LoL matches, you should continue reading to gather additional tricks and insights into this champion pairing. If you pay attention to the build and stats shown here, you should grow your win rate by a lot.
The best finished items to prioritize in your Senna and Lee Sin synergy build consist of Youmuu's Ghostblade, Edge of Night, and Bloodsong. When Senna bought at least these three finished items in her build, she performed significantly better when fighting alongside Lee Sin than with most other typical builds. In fact, Senna boasted an average winrate of 48.1% helping carry Lee Sin with these items in her kit.
To have the best probability of defeating your oponents, you should use the Fleet Footwork, Presence of Mind, Legend: Alacrity, Cut Down, Biscuit Delivery, and Approach Velocity runes from the Precision and Inspiration rune sets. Out of all the rune sets players picked for Senna and Lee Sin pairings, this sequence of runes resulted in the top win rate. In fact, these runes provided a 48.1% winrate overall.
By default, tips, statistics, and builds on how to team up Lee Sin with Senna are presented for all ranked divisions combined. To scope the statistics and builds to an individual skill level, you should use the selection menu located above.