Kassadin's ultimate has many uses and is on a shorter cooldown than most, use it often.
Kassadin has multiple item paths; he can go caster via Mana and Ability Power or anti-caster with Cooldown Reduction and Magic Resist.
Try to get the Ancient Golem buff to counteract Riftwalk's increasing Mana cost.
The Senna Kassadin synergy stats shown here demonstrate the areas of her gameplay that do better (or worse) when paired with Kassadin, compared to her overall stats. Significant differences are areas of focus that highlight how her gameplay changes when paired with this other champion.
Overall, Senna sees a large worsening in her KDA (ratio of kills and assists to deaths) when paired with Kassadin. His KDA fell from NaN to NaN. This worsening shows that Kassadin helps Senna perform worse in ranked League of Legends matches. Yet, the small difference demonstrates that this performance change is not very impactful.
When Senna tries to synergize with Kassadin, she gets a small decrease in her full damage dealt. This could indicate that Kassadin does not support by providing cover for her to deal more damage or that his participation also helps extend the match's duration. Similarly, when Senna is played together with Kassadin on the same team, he usually scores many fewer killing sprees than when she plays without Kassadin. This is contrasting evidence that she is worse when playing synergisticly with Kassadin.
Moreover, when Senna plays with Kassadin on the same side, she on average takes a little less damage than when she fights alone. Taking not as much damage could indicate that Kassadin does a decent job of protecting Senna during team fights.
There is no universally accepted best companion for Senna that will always be her ideal ally. Yet, Kassadin is a very typical companion for Senna. By playing on the same team as Senna, he drops their win rate by -0.8% to 50.0%. This shows that there is only a small synergy between Senna and Kassadin that results in them performing not as well together than alone.
Kassadin has a greater difficulty than Senna. That means you should be careful when finding Kassadin teammates to fight alongside, as they will require a greater level of skill to be able to work well with you.
Working cooperatively, you should witness an overall large increase in your team’s capability to deal magic damage. Combined, these champs can deal quite a lot of AP type damage.
Although, by grouping Senna and Kassadin together, you may not be providing your side very much engage. Plan to pick other champions on your team that offsets this relative gap in this pairing's abilities.
Regardless of the ability of your Kassadin ally, you need to focus on increasing your income, outlasting your enemies, and taking down objectives. If you follow these simple suggestions, you should do well, regardless.
If you would like to learn all of the intricacies of Senna to synergize with Kassadin during both the laning and mid / late game phases of LoL matches, you should continue reading to master some more tips and tricks for this champion pairing. If you mind the build and stats shown above, you will grow your win rate by a lot.
The top finished items to prioritize in your Senna and Kassadin synergy build include Lord Dominik's Regards, Rapid Firecannon, and Bloodsong. When Senna incorporated at least these three finished items in her build, she performed a lot better as an ally of Kassadin than with most other commonly used item sets. In fact, Senna had an average winrate of 50.0% when synergizing her build and playstyle to Kassadin with this build.
To have the best chance of beating your oponents, Senna players should use the Fleet Footwork, Presence of Mind, Legend: Alacrity, Cut Down, Bone Plating, and Revitalize runes from the Precision and Resolve rune sets. Of all the rune combinations players picked for this champion pairing, this sequence of runes yielded the top win rate. In fact, these runes gave a 50.0% winrate overall.
By default, tips, statistics, and builds on how to pair Kassadin with Senna are shown for all skill levels combined. If you want to narrow the statistics and builds to a particular division, you can use the selection menu located above.