Spell Flux's short cooldown allows it to be used to spread Flux to many enemies.
Use Overload's passive to optimize for maximum damage or maximum speed.
Ryze can move and cast other spells while Realm Warp is charging without cancelling the portal.
Transfusion instantly deals damage to the enemy before healing Vladimir, making it one of the best last hitting tools in the game.
Cast Hemoplague where it will afflict the most units.
Sanguine Pool pops incoming missiles, so it can be used to dodge disables.
The Ryze Vladimir synergy stats shown here demonstrate the areas of his gameplay that do better (or worse) when paired with Vladimir, compared to his overall stats. Significant differences are areas of focus that highlight how his gameplay changes when paired with this other champion.
Overall, Ryze sees a very large drop in his KDA (ratio of kills and assists to deaths) when paired with Vladimir. His KDA decreased from NaN to NaN. This negative change shows that Vladimir helps Ryze perform not as well in ranked League of Legends matches. Yet, the small difference shows that this performance change is not very impactful.
When Ryze is an ally to Vladimir, he gets a small decrease in his complete damage dealt. This change could signal that Vladimir does not support by providing protection for him to deal more damage or that his allyship also helps increase the round's duration. Similarly, when Ryze is played together with Vladimir on the same team, he usually scores many fewer killing sprees compared to when he plays on his own. This is contrasting evidence that he is worse when playing with Vladimir.
Moreover, when Ryze plays with Vladimir on the same team, he usually receives a little more damage than when he plays alone. Getting dealt more damage may indicate that Vladimir does a poor job of protecting Ryze in teamfights.
There is no ideal champion pairing for Ryze that will 100% of the time be his best synergy. However, Vladimir is a relatively poor teammate for Ryze. By being on the same team as Ryze, he drops their win rate by -3.0% to 46.0%. This clearly indicates that there is a harmful bond between Ryze and Vladimir that allows them to perform worse together than alone.
Vladimir has a lower difficulty than Ryze. That means you don't need to be cautious when finding Vladimir comrades to fight alongside, as they will need a lower level of skill to play well with you.
Playing together, Ryze players should expect to witness an overall large increase in your team’s capability to deal magical damage. When paired, these champs can deal quite a lot of AP type damage.
Although, by pairing Ryze and Vladimir together, you may not be giving your other teammates much sustained damage output. Make sure to have other champions on your team that fills this relative hole in this pairing's kit.
Regardless of the ability of your Vladimir teammate, you should focus on increasing your income, outlasting your enemies, and taking down objectives. If you heed this simple advice, you will do well anyway.
To learn all of the intricacies of Ryze to pair well with Vladimir during both the early game and mid / late game phases of League, you should keep reading to master additional tricks and insights into this champion pairing. If you use the build and tips shown above, you will increase your win rate significantly.
The top finished items to build first in your Ryze and Vladimir synergy build consist of Seraph's Embrace, Rabadon's Deathcap, and Rod of Ages. When Ryze included at least these three finished items in his build, he performed a lot better when fighting alongside Vladimir than with most other typical builds. In fact, Ryze had an average win rate of 46.0% helping carry Vladimir with these items in his kit.
To have the highest likelihood of vanquishing your oponents, you should use the Phase Rush, Manaflow Band, Transcendence, Gathering Storm, Bone Plating, and Overgrowth runes from the Sorcery and Resolve rune sets. Of all the rune builds players chose for Ryze and Vladimir pairings, this order of runes resulted in the greatest win rate. Moreover, these runes gave a 46.0% winrate overall.
By default, tips, stats, and builds on how to team up Vladimir with Ryze are presented for all skill levels combined. To scope the statistics and builds to a specific skill level, you can use the selection menu located above.