Spell Flux's short cooldown allows it to be used to spread Flux to many enemies.
Use Overload's passive to optimize for maximum damage or maximum speed.
Ryze can move and cast other spells while Realm Warp is charging without cancelling the portal.
Kassadin's ultimate has many uses and is on a shorter cooldown than most, use it often.
Kassadin has multiple item paths; he can go caster via Mana and Ability Power or anti-caster with Cooldown Reduction and Magic Resist.
Try to get the Ancient Golem buff to counteract Riftwalk's increasing Mana cost.
The Ryze Kassadin synergy stats shown here demonstrate the areas of his gameplay that do better (or worse) when paired with Kassadin, compared to his overall stats. Significant differences are areas of focus that highlight how his gameplay changes when paired with this other champion.
Overall, Ryze sees a very large drop in his KDA (ratio of kills and assists to deaths) when paired with Kassadin. His KDA went down from NaN to NaN. This negative change shows that Kassadin helps Ryze perform worse in competitive League matches. Yet, the small difference proves that this performance change is not very impactful.
When Ryze tries to synergize with Kassadin, he gets a barely noticable drop in his complete damage output. This change may indicate that Kassadin does not provide protection for him to deal more damage or that his presence also helps increase the round's duration. Similarly, when Ryze is played alongside Kassadin on the same side, he usually scores many fewer killing sprees than when he plays on his own. This is contrasting evidence that he is worse when playing with Kassadin.
Additionally, when Ryze plays with Kassadin on the same team, he typically takes a little more damage than when he fights alone. Receiving more damage may indicate that Kassadin does a poor job of protecting Ryze in teamfights.
There is no top companion for Ryze that will no matter what be his #1 teammate. However, Kassadin is a not very good ally for Ryze. By locking into the same side as Ryze, he drops their win rate by -2.7% to 46.3%. This shows that there is a harmful bond between Ryze and Kassadin that results in them performing worse together than alone.
Kassadin has a greater difficulty than Ryze. That means you should be careful when lining up Kassadin allies to fight alongside, as they will require a greater level of skill to be able to cooperate well with you.
Working on the same side, you will likely see an overall large increase in your team’s capability to to do a lot of AP damage. Combined, these champs can deal quite a lot of AP type damage.
Although, by pairing Ryze and Kassadin together, you may not be granting your other allies enough attack damage. Make sure to have other champions on your team that nullifies this gap in this pairing's potential.
Regardless of your Kassadin ally's ability, you need to focus on maximizing your gold income, warding to avoid ambushes, and taking down objectives. If you heed this simple advice, you should do well anyway.
To learn all of the intricacies of Ryze to work well with Kassadin during both the lane and mid / late game phases of League rounds, you should continue reading to gather some more lessons on this champion pairing. If you mind the build and tips presented above, you will increase your win rate by a lot.
The top finished items to have in your Ryze and Kassadin synergy build consist of Seraph's Embrace, Rabadon's Deathcap, and Luden's Companion. When Ryze bought at least these three items in his build, he did a lot better when fighting alongside Kassadin than with most other commonly used item sets. In fact, Ryze boasted an average winrate of 46.3% helping carry Kassadin with these items in his kit.
To have the best chance of coming out on top against your oponents, you should equip the Phase Rush, Manaflow Band, Transcendence, Scorch, Bone Plating, and Overgrowth runes from the Sorcery and Resolve rune sets. Of all the rune combinations players chose for Ryze and Kassadin pairings, this composite of runes yielded the best win rate. Notably, these runes provided a 46.3% win rate overall.
If you need to see Ryze and Kassadin synergy tips and stats for a a particular division rank, feel free to select one from the selection menu shown above. By default, the stats and build suggestions given are calculated using every match finished with both champions.