Spell Flux's short cooldown allows it to be used to spread Flux to many enemies.
Use Overload's passive to optimize for maximum damage or maximum speed.
Ryze can move and cast other spells while Realm Warp is charging without cancelling the portal.
Lay Waste is very strong at farming minions and harassing enemy champions.
Ask your allies to help point out when you should use Requiem to get kills in different lanes.
The Ryze Karthus synergy stats shown here demonstrate the areas of his gameplay that do better (or worse) when paired with Karthus, compared to his overall stats. Significant differences are areas of focus that highlight how his gameplay changes when paired with this other champion.
Overall, Ryze sees a large worsening in his KDA (ratio of kills and assists to deaths) when paired with Karthus. His KDA fell from NaN to NaN. This fall shows that Karthus helps Ryze perform worse in competitive LoL matches. Yet, the small difference proves that this performance change is not very impactful.
When Ryze plays on the same team as Karthus, he observes a little decrease in his full damage output. This may signal that Karthus does not provide cover for him to dish out more damage or that his support also helps extend the match's duration. Similarly, when Ryze is played together with Karthus on the same side, he usually scores many fewer killing sprees compared to when he plays alone. This is contrasting evidence that he is worse when playing alongside Karthus.
Moreover, when Ryze plays with Karthus on the same team, he on average takes more damage than when he plays alone. Getting dealt more damage could indicate that Karthus does a poor job of covering Ryze during teamfights.
There is no one best ally for Ryze that will 100% of the time be his best ally. Yet, Karthus is a terrible teammate for Ryze. By playing on the same team as Ryze, he drops their win rate by -7.9% to 41.1%. This demonstrates that there is an easy to overcome and exploit bond between Ryze and Karthus that allows them to perform not as well together than without each other.
Karthus has a lower difficulty than Ryze. That means you don't need to be cautious when arranging Karthus teammates to play with, as they will need a lower level of skill to be able to do well with you.
Working together, Ryze players will likely observe an overall large increase in your team’s capacity to deal magic damage. Combined, these two can blast through enemies with magic damage.
Although, by pairing Ryze and Karthus together, you may not be giving your other allies enough attack damage. We recommend you have other champs on your team that nullifies this relative gap in this pairing's kit.
Regardless of your Karthus ally's ability, you should focus on maximizing your gold income, warding to avoid ambushes, and clearing objectives. If you do this, you should do well anyway.
If you would like to learn all of the intricacies of Ryze in order to synergize with Karthus during both the early game and mid / late game phases of League of Legends games, you should continue reading to master some more lessons on this champion pairing. If you listen to the build and tips displayed above, you will increase your win rate by a lot.
The ideal finished items to focus on in your Ryze and Karthus synergy build consist of Seraph's Embrace, Rabadon's Deathcap, and Rod of Ages. When Ryze bought at least these three great items in his build, he did a lot better when paired up with Karthus than with most other typical item sets. In fact, Ryze boasted an average win rate of 41.1% when synergizing his build and playstyle to Karthus with this build.
To have the highest likelihood of crushing your oponents, you should equip the Phase Rush, Manaflow Band, Transcendence, Gathering Storm, Bone Plating, and Overgrowth runes from the Sorcery and Resolve rune sets. Out of all the rune sets that we analyzed for this team composition, this combo of runes yielded the greatest win rate. Moreover, these runes averaged a 41.1% winrate overall.
By default, tips, stats, and builds on how to synergize Karthus with Ryze are displayed for all ranked divisions. To filter the statistics and builds to a distinct rank, you should use the selection menu earlier on the page.