Lay Waste is very strong at farming minions and harassing enemy champions.
Ask your allies to help point out when you should use Requiem to get kills in different lanes.
The Renata Glasc Karthus synergy stats shown here demonstrate the areas of their gameplay that do better (or worse) when paired with Karthus, compared to their overall stats. Significant differences are areas of focus that highlight how their gameplay changes when paired with this other champion.
Overall, Renata Glasc sees a large worsening in their KDA (ratio of kills and assists to deaths) when paired with Karthus. His KDA decreased from NaN to NaN. This decrease shows that Karthus helps Renata Glasc perform poorer in ranked League matches. Yet, the small difference shows that this performance change is only marginal.
When Renata Glasc tries to synergize with Karthus, they sees a little increase in their total damage dealt. This difference may indicate that Karthus helps provide cover for them to deal more damage or that his support also helps increase the match's duration. Similarly, when Renata Glasc is played alongside Karthus on the same side, he usually scores many fewer killing sprees compared to when they plays alone. This is contrasting evidence that they is worse when playing synergisticly with Karthus.
Moreover, when Renata Glasc plays with Karthus on the same side, they often takes more damage than when they plays alone. Receiving more damage could indicate that Karthus does a poor job of protecting Renata Glasc in teamfights.
There is no universally accepted best synergy for Renata Glasc that will 100% of the time be their ideal teammate. However, overall, Karthus is a not very good ally for Renata Glasc. By locking into the same side as Renata Glasc, he drops their win rate by -1.3% to 48.5%. This signals that there is a negative bond between Renata Glasc and Karthus that results in them performing not as well together than alone.
Karthus has a lower difficulty than Renata Glasc. That means Renata Glasc players don't need to be cautious when finding Karthus comrades to go into battle on the same side as, as they will need a relatively low level of skill to be able to work well with you.
Playing alongside, Renata Glasc players will likely see an overall large increase in your team’s capacity to deal magical damage. When paired, these two can blast through enemies with magic damage.
Conversely, by aligning Renata Glasc and Karthus together, you may not be granting your other allies a lot of sustained damage output. Make sure to bring other champions on your team that nullifies this disparity in this pairing's kit.
Regardless of your Karthus ally's skill level, you need to focus on increasing your income, outlasting your enemies, and taking down objectives. If you do this, you will do well, regardless.
To truly master Renata Glasc in order to work well with Karthus during both the lane and mid / late game phases of League of Legends matches, you should continue reading to gather a few extra tricks and insights into this champion pairing. If you use the build and stats displayed here, you will increase your win rate significantly.
The most important finished items to use in your Renata Glasc and Karthus synergy build include Shurelya's Battlesong, Redemption, and Dream Maker. When Renata Glasc incorporated at least these three great items in their build, they performed a lot better when paired up with Karthus than with many other typical builds. In fact, Renata Glasc boasted an average winrate of 48.5% helping carry Karthus with this build.
To have the greatest chance of beating your oponents, you should use the Guardian, Shield Bash, Bone Plating, Unflinching, Relentless Hunter, and Zombie Ward runes from the Resolve and Domination rune sets. Out of all the rune sets players chose for Renata Glasc and Karthus pairings, this sequence of runes yielded the highest win rate. Notably, these runes averaged a 48.5% winrate overall.
By default, tips, stats, and builds on how to team up Karthus with Renata Glasc are shown for all skill levels, merged. If you would like to narrow the statistics and builds to a distinct skill level, you may use the selection menu above.