Lay Waste is very strong at farming minions and harassing enemy champions.
Ask your allies to help point out when you should use Requiem to get kills in different lanes.
The Qiyana Karthus synergy stats shown here demonstrate the areas of her gameplay that do better (or worse) when paired with Karthus, compared to her overall stats. Significant differences are areas of focus that highlight how her gameplay changes when paired with this other champion.
Overall, Qiyana sees a very large drop in her KDA (ratio of kills and assists to deaths) when paired with Karthus. His KDA went down from NaN to NaN. This decrease shows that Karthus helps Qiyana perform poorer in ranked League of Legends games. Yet, the small difference proves that this performance change is only marginal.
When Qiyana is paired with Karthus, she sees a little increase in her full damage output. This change may signal that Karthus provides cover for her to dish out more damage or that his presence on the team also helps increase the game's duration. Similarly, when Qiyana is played with Karthus on the same side, he usually scores many fewer killing sprees compared to when she plays without Karthus. This is contrasting evidence that she is worse when playing with Karthus.
Additionally, when Qiyana plays with Karthus on the same team, she on average takes a little more damage than when she fights alone. Taking more damage could indicate that Karthus does a poor job of protecting Qiyana in teamfights.
There is no ideal companion for Qiyana that will no matter what be her best synergy. Yet, overall, Karthus is a relatively poor companion for Qiyana. By being on the same side as Qiyana, he drops their win rate by -1.8% to 46.0%. This shows that there is a harmful bond between Qiyana and Karthus that results in them performing worse together than alone.
Karthus has a lower difficulty than Qiyana. That means Qiyana players don't need to be careful when finding Karthus allies to play with, as they will need a lower level of skill to be able to fight well with you.
Playing alongside, you will likely see an overall large increase in your team’s ability to deal magical damage. Combined, these champs are able to dish out a surprising amount of magic type damage.
In contrast, by aligning Qiyana and Karthus together, you probably will not be providing your team very much AD. Plan to include other champions on your team that neutralizes this relative gap in their kit.
Regardless of your Karthus ally's ability, you need to focus on maximizing your gold income, staying alive by avoiding foolish fights, and taking down objectives. If you do this, you should do well anyway.
To learn all of the intricacies of Qiyana to synergize with Karthus during both the lane and mid / late game phases of League of Legends games, you should keep reading to pick up a few extra tricks and insights into this champion pairing. If you pay attention to the build and suggestions presented here, you should grow your win rate significantly.
The ideal items to have in your Qiyana and Karthus synergy build include Youmuu's Ghostblade, Serylda's Grudge, and Axiom Arc. When Qiyana incorporated at least these three great items in her build, she did significantly better when fighting alongside Karthus than with most other commonly used builds. In fact, Qiyana had an average win rate of 46.0% helping carry Karthus with these items in her kit.
To have the highest probability of coming out on top against your oponents, Qiyana players should take the Electrocute, Sudden Impact, Eyeball Collection, Treasure Hunter, Presence of Mind, and Last Stand runes from the Domination and Precision rune sets. Out of all the rune builds players used for Qiyana and Karthus pairings, this combination of runes yielded the top win rate. Notably, these runes gave a 46.0% win rate overall.
By default, tips, statistics, and builds on how to team up Karthus with Qiyana are presented for all skill levels combined. To filter the statistics and builds to an individual skill level, you may use the selection menu located at the top of this page.