Lead your enemy when targeting with Noxious Blast to ensure the hit.
Use Twin Fang on poisoned stationary targets like monsters and units stunned by her Petrifying Gaze for maximum damage.
The Qiyana Cassiopeia synergy stats shown here demonstrate the areas of her gameplay that do better (or worse) when paired with Cassiopeia, compared to her overall stats. Significant differences are areas of focus that highlight how her gameplay changes when paired with this other champion.
Overall, Qiyana sees a large worsening in her KDA (ratio of kills and assists to deaths) when paired with Cassiopeia. His KDA decreased from NaN to NaN. This decrease shows that Cassiopeia helps Qiyana perform poorer in competitive League of Legends rounds. Yet, the small difference indicates that this performance change is not very impactful.
When Qiyana is an ally to Cassiopeia, she observes a small decrease in her full damage output. This may signal that Cassiopeia doesn't help protection for her to deal more damage or that her participation also helps increase the round's duration. Similarly, when Qiyana is played alongside Cassiopeia on the same team, he usually scores many fewer killing sprees compared to when she plays on his own. This is contrasting evidence that she is worse when playing synergisticly with Cassiopeia.
Additionally, when Qiyana plays with Cassiopeia on the same team, she typically takes a little more damage than when she plays alone. Taking more damage may indicate that Cassiopeia does a poor job of protecting Qiyana in teamfights.
There is no one best synergy for Qiyana that will no matter what be her best teammate. Yet, Cassiopeia is a below average companion for Qiyana. By playing on the same team as Qiyana, she decreases their win rate by -2.2% to 45.6%. This clearly indicates that there is a bad bond between Qiyana and Cassiopeia that results in them performing not as well together than alone.
Cassiopeia has a greater difficulty than Qiyana. That means you should be cautious when arranging Cassiopeia teammates to go into battle on the same side as, as they will need a greater level of skill to be able to cooperate well with you.
Fighting together, you will likely observe an overall large increase in your team’s capacity to deal magic damage. Combined, these champs can deal quite a lot of AP type damage.
In contrast, by grouping Qiyana and Cassiopeia together, you may not be granting your other teammates very much sustained damage output. We recommend you include other champions on your team that neutralizes this relative hole in their capabilities.
Regardless of your Cassiopeia ally's skill level, you should focus on increasing your gold income, warding to avoid ambushes, and clearing objectives. If you do this, you will do well, regardless.
If you would like to learn all of the intricacies of Qiyana to synergize with Cassiopeia during both the laning and mid / late game phases of League of Legends matches, you should continue reading to pick up some more tips and tricks for this champion pairing. If you pay attention to the build and tips shown above, you will grow your win rate significantly.
The most crucial finished items to focus on in your Qiyana and Cassiopeia synergy build include Serylda's Grudge, Profane Hydra, and Opportunity. When Qiyana used at least these three items in her build, she performed significantly better when fighting alongside Cassiopeia than with many other commonly used item sets. In fact, Qiyana had an average winrate of 45.6% when synergizing her build and playstyle to Cassiopeia with these items in her kit.
To have the greatest probability of defeating your oponents, Qiyana players should equip the Electrocute, Sudden Impact, Eyeball Collection, Treasure Hunter, Last Stand, and Presence of Mind runes from the Domination and Precision rune sets. Of all the rune sets that we analyzed for this champion pairing, this combo of runes resulted in the highest win rate. In fact, these runes averaged a 45.6% win rate overall.
By default, tips, stats, and builds on how to team up Cassiopeia with Qiyana are given for all ranked divisions combined. If you want to narrow the statistics and builds to an individual rank, you should use the selection menu above.