Mortal Will activates after 5 spells or basic attacks - plan your way through fights to allow you to activate it more than once.
Whittle the enemy down with Comet Spears before you jump in.
If an enemy is going to get out of range of your Aegis Assault, you can recast the spell to immediately fire the shield slam.
Don't go in first to a large teamfight. Wait for your teammates to initiate.
Tumble has many uses, but it cannot pass over walls.
Condemn can be used to both pin targets to walls to ensure a kill, or to escape a pursuer.
The Pantheon Vayne synergy stats shown here demonstrate the areas of his gameplay that do better (or worse) when paired with Vayne, compared to his overall stats. Significant differences are areas of focus that highlight how his gameplay changes when paired with this other champion.
Overall, Pantheon sees a very large drop in his KDA (ratio of kills and assists to deaths) when paired with Vayne. His KDA fell from NaN to NaN. This worsening shows that Vayne helps Pantheon perform not as well in competitive League rounds. Yet, the small difference shows that this performance change is only marginal.
When Pantheon tries to synergize with Vayne, he observes a little drop in his total damage output. This difference could indicate that Vayne does not support by providing cover for him to deal more damage or that her presence on the team also helps extend the match's duration. Similarly, when Pantheon is played together with Vayne on the same team, he usually scores many fewer killing sprees compared to when he plays alone. This is contrasting evidence that he is worse when playing with Vayne.
Additionally, when Pantheon plays with Vayne on the same team, he typically takes a little less damage than when he fights alone. Taking not as much damage could mean that Vayne does a decent job of covering Pantheon in teamfights.
There is no one best champion pairing for Pantheon that will 100% of the time be his top ally. Yet, overall, Vayne is a very typical teammate for Pantheon. By locking into the same side as Pantheon, she lowers their win rate by -0.6% to 48.8%. This signals that there is only a small bond between Pantheon and Vayne that allows them to perform worse together than without each other.
Vayne has a much greater difficulty compared to Pantheon. That means Pantheon players need to be very careful when enlisting Vayne comrades to go into battle on the same side as, as they will require a much higher level of skill to be able to cooperate well with you.
Working alongside, you will likely witness an overall large increase in your team’s capability to dish out massive AD. When paired, these two can provide a great amount of sustained physical damage.
In contrast, by pairing Pantheon and Vayne together, you will not be giving your other teammates very much AP. Make sure to pick other champs on your team that helps cover this relative hole in this pairing's capabilities.
Regardless of your Vayne ally's ability, you need to focus on maximizing your income, staying alive by avoiding foolish fights, and taking down objectives. If you follow these simple suggestions, you should do well, regardless.
To learn all of the intricacies of Pantheon to pair well with Vayne during both the laning and mid / late game phases of LoL matches, you should keep reading to pick up a few extra lessons on this champion pairing. If you use the build and tips displayed here, you should increase your win rate by a lot.
The most crucial items to use in your Pantheon and Vayne synergy build include Black Cleaver, Death's Dance, and Eclipse. When Pantheon combined at least these three finished items in his build, he did a lot better as an ally of Vayne than with many other common item sets. In fact, Pantheon had an average win rate of 48.8% when playing alongside Vayne with these items in his kit.
To have the greatest chance of defeating your oponents, Pantheon players should take the Press the Attack, Triumph, Legend: Tenacity, Coup de Grace, Cosmic Insight, and Hextech Flashtraption runes from the Precision and Inspiration rune sets. Out of all the rune builds players used for Pantheon and Vayne pairings, this combo of runes yielded the highest win rate. In fact, these runes provided a 48.8% winrate overall.
If you want to view Pantheon and Vayne cooperations tips and builds for a a specific player tier, feel free to select one from the selection menu displayed above. By default, the statistics and tips and suggestions given are computed using all matches with data with both champions.