Mortal Will activates after 5 spells or basic attacks - plan your way through fights to allow you to activate it more than once.
Whittle the enemy down with Comet Spears before you jump in.
If an enemy is going to get out of range of your Aegis Assault, you can recast the spell to immediately fire the shield slam.
Contaminate has a large range; apply as many stacks of Deadly Venom as possible before using it.
You can catch up to an enemy out of attack range with Venom Cask.
Twitch's Attack Speed is among the highest in the game; try purchasing items with on-hit effects such as Black Cleaver or Wit's End.
The Pantheon Twitch synergy stats shown here demonstrate the areas of his gameplay that do better (or worse) when paired with Twitch, compared to his overall stats. Significant differences are areas of focus that highlight how his gameplay changes when paired with this other champion.
Overall, Pantheon sees a large worsening in his KDA (ratio of kills and assists to deaths) when paired with Twitch. His KDA worsened from NaN to NaN. This negative change shows that Twitch helps Pantheon perform not as well in ranked League games. Yet, the small difference demonstrates that this performance change is only marginal.
When Pantheon tries to synergize with Twitch, he sees a little increase in his full damage dealt. This may signal that Twitch provides cover for him to deal more damage or that his support also helps extend the match's duration. Similarly, when Pantheon is played alongside Twitch on the same side, he usually scores many fewer killing sprees compared to when he plays without Twitch. This is contrasting evidence that he is worse when playing synergisticly with Twitch.
Moreover, when Pantheon plays with Twitch on the same team, he often takes a little more damage than when he plays alone. Getting dealt more damage may mean that Twitch does a poor job of covering Pantheon during teamfights.
There is no ideal companion for Pantheon that will 100% of the time be his ideal ally. However, Twitch is a very typical ally for Pantheon. By playing on the same team as Pantheon, he lowers their win rate by -0.2% to 49.2%. This clearly indicates that there is only a small bond between Pantheon and Twitch that allows them to perform not as well together than alone.
Twitch has a greater difficulty than Pantheon. That means you should be careful when enlisting Twitch comrades to fight alongside, as they will need a greater level of skill to be able to cooperate well with you.
Working alongside, Pantheon players should expect to witness an overall large increase in your team’s capacity to dish out massive AD. Combined, these two can provide a great amount of sustained physical damage.
In contrast, by aligning Pantheon and Twitch together, you probably will not be granting your side a great deal of AP. Plan to bring other champions on your team that neutralizes this gap in their abilities.
Regardless of your Twitch ally's skill level, you need to focus on increasing your gold income, outlasting your enemies, and taking down objectives. If you follow these simple suggestions, you will do well, regardless.
To truly master Pantheon in order to synergize with Twitch during both the laning and mid / late game phases of LoL, you should continue reading to gather a few extra tips and tricks for this champion pairing. If you pay attention to the build and tips displayed above, you will grow your win rate significantly.
The top finished items to get in your Pantheon and Twitch synergy build include Sterak's Gage, Sundered Sky, and Eclipse. When Pantheon combined at least these three finished items in his build, he did significantly better when paired up with Twitch than with most other common item sets. In fact, Pantheon had an average winrate of 49.2% when synergizing his build and playstyle to Twitch with these items in his kit.
To have the highest probability of defeating your oponents, you should use the Conqueror, Triumph, Legend: Tenacity, Coup de Grace, Cheap Shot, and Relentless Hunter runes from the Precision and Domination rune sets. Out of all the rune combinations players used for this team composition, this set of runes resulted in the greatest win rate. Moreover, these runes averaged a 49.2% winrate overall.
If you want to view Pantheon and Twitch collaboration tips and builds for a a specific division rank, please select one from the selection menu shown above. At first, the stats and build suggestions given are calculated using all rounds completed with both champs.