Mortal Will activates after 5 spells or basic attacks - plan your way through fights to allow you to activate it more than once.
Whittle the enemy down with Comet Spears before you jump in.
If an enemy is going to get out of range of your Aegis Assault, you can recast the spell to immediately fire the shield slam.
The Pantheon Seraphine synergy stats shown here demonstrate the areas of his gameplay that do better (or worse) when paired with Seraphine, compared to his overall stats. Significant differences are areas of focus that highlight how his gameplay changes when paired with this other champion.
Overall, Pantheon sees a very large drop in his KDA (ratio of kills and assists to deaths) when paired with Seraphine. His KDA went down from NaN to NaN. This drop shows that Seraphine helps Pantheon perform not as well in competitive League of Legends matches. Yet, the small difference demonstrates that this performance change is only marginal.
When Pantheon tries to synergize with Seraphine, he gets a small increase in his total damage output. This difference may demonstrate that Seraphine provides cover for him to deal more damage or that her support also helps increase the round's duration. Similarly, when Pantheon is played alongside Seraphine on the same side, he usually scores many fewer killing sprees compared to when he plays alone. This is contrasting evidence that he is worse when playing synergisticly with Seraphine.
Additionally, when Pantheon plays with Seraphine on the same side, he often takes a little more damage than when he fights alone. Receiving more damage could mean that Seraphine does a poor job of covering Pantheon during teamfights.
There is no perfect ally for Pantheon that will always be his #1 synergy. Yet, Seraphine is a very typical teammate for Pantheon. By being on the same team as Pantheon, she improves their win rate by 0.8% to 50.2%. This demonstrates that there is only a small synergy between Pantheon and Seraphine that results in them performing at the top of their game together than without each other.
Seraphine has a much lower diffuclty than Pantheon. That means you don't need to be careful when lining up Seraphine allies to fight alongside, as they will require a much lower level of skill to be able to cooperate well with you.
Fighting alongside, you will likely witness an overall large increase in your team’s capacity to provide a lot of utility for your team. Together, these two will help their other teammates secure a victory.
In contrast, by grouping Pantheon and Seraphine together, you will not be granting your side a lot of AP. Make sure to have other champs on your team that helps cover this relative disparity in this pairing's potential.
Regardless of your Seraphine ally's skill level, you need to focus on maximizing your gold income, outlasting your enemies, and taking down objectives. If you do this, you will do well, regardless.
If you would like to truly master Pantheon in order to synergize with Seraphine during both the laning and mid / late game phases of League of Legends rounds, you should continue reading to learn a few extra tricks and insights into this champion pairing. If you listen to the build and suggestions displayed here, you will increase your win rate by a lot.
The most crucial finished items to include in your Pantheon and Seraphine synergy build include Blade of The Ruined King, Serylda's Grudge, and Opportunity. When Pantheon combined at least these three pieces in his build, he did much better when fighting alongside Seraphine than with many other typical item sets. In fact, Pantheon had an average winrate of 50.2% helping carry Seraphine with these items in his kit.
To have the greatest probability of defeating your oponents, Pantheon players should equip the Press the Attack, Triumph, Legend: Tenacity, Coup de Grace, Cheap Shot, and Relentless Hunter runes from the Precision and Domination rune sets. Of all the rune builds players used for this team composition, this combination of runes yielded the highest win rate. In fact, these runes averaged a 50.2% winrate overall.
If you would like to get Pantheon with Seraphine synergy tips and builds for a a particular player tier, feel free to choose one from the selection menu provided above. At first, the statistics and guides given are computed using all rounds finished with these champs.