Mortal Will activates after 5 spells or basic attacks - plan your way through fights to allow you to activate it more than once.
Whittle the enemy down with Comet Spears before you jump in.
If an enemy is going to get out of range of your Aegis Assault, you can recast the spell to immediately fire the shield slam.
Lead your enemy when targeting with Noxious Blast to ensure the hit.
Use Twin Fang on poisoned stationary targets like monsters and units stunned by her Petrifying Gaze for maximum damage.
The Pantheon Cassiopeia synergy stats shown here demonstrate the areas of his gameplay that do better (or worse) when paired with Cassiopeia, compared to his overall stats. Significant differences are areas of focus that highlight how his gameplay changes when paired with this other champion.
Overall, Pantheon sees a very large drop in his KDA (ratio of kills and assists to deaths) when paired with Cassiopeia. His KDA went down from NaN to NaN. This worsening shows that Cassiopeia helps Pantheon perform worse in ranked League matches. Yet, the small difference demonstrates that this performance change is only marginal.
When Pantheon is an ally to Cassiopeia, he gets a little increase in his complete damage dealt. This change could indicate that Cassiopeia provides protection for him to dish out more damage or that her support also helps extend the match's duration. Similarly, when Pantheon is played alongside Cassiopeia on the same team, he usually scores many fewer killing sprees than when he plays without Cassiopeia. This is contrasting evidence that he is worse when playing with Cassiopeia.
Additionally, when Pantheon plays with Cassiopeia on the same team, he usually receives a little less damage than when he fights alone. Taking not as much damage may indicate that Cassiopeia does a decent job of protecting Pantheon in teamfights.
There is no universally accepted best companion for Pantheon that will 100% of the time be his best synergy. However, Cassiopeia is a top-tier teammate for Pantheon. By locking into the same team as Pantheon, she increases their win rate by 3.7% to 53.1%. This shows that there is an important strategic relationship between Pantheon and Cassiopeia that allows them to perform at the top of their game together than without each other.
Cassiopeia has a much greater difficulty compared to Pantheon. That means you must be very careful when arranging Cassiopeia allies to go into battle on the same side as, as they will need a much greater level of skill to be able to do well with you.
Playing alongside, Pantheon players should expect to see an overall large increase in your team’s capacity to deal magical damage. Together, these champs are able to dish out a surprising amount of magic type damage.
Conversely, by grouping Pantheon and Cassiopeia together, you may not be giving your team enough engage. Plan to pick other champs on your team that nullifies this relative gap in this pairing's abilities.
Regardless of your Cassiopeia ally's ability, you should focus on increasing your income, warding to avoid ambushes, and taking down objectives. If you do this, you should do well anyway.
If you would like to learn all of the intricacies of Pantheon in order to synergize with Cassiopeia during both the early game and mid / late game phases of League, you should keep reading to gather some more tips and tricks for this champion pairing. If you use the build and suggestions shown here, you will increase your win rate significantly.
The top finished items to have in your Pantheon and Cassiopeia synergy build consist of Black Cleaver, Sundered Sky, and Eclipse. When Pantheon incorporated at least these three items in his build, he did significantly better as an ally of Cassiopeia than with many other commonly used item sets. In fact, Pantheon had an average winrate of 53.1% when synergizing his build and playstyle to Cassiopeia with this build.
To have the greatest probability of vanquishing your oponents, Pantheon players should take the Press the Attack, Triumph, Legend: Tenacity, Coup de Grace, Sudden Impact, and Treasure Hunter runes from the Precision and Domination rune sets. Out of all the rune sets that we analyzed for this champion pairing, this mix of runes resulted in the best win rate. In fact, these runes gave a 53.1% winrate overall.
By default, tips, stats, and builds on how to synergize Cassiopeia with Pantheon are presented for all skill levels combined. If you want to scope the stats and builds to a distinct player tier, you can use the selection menu earlier in the counter matchup guide.