Command: Protect can be used on yourself to return the Ball back to you quickly. Combine this with Command: Attack for a quick harassment.
Command: Dissonance is a very powerful escape tool if Orianna has the Ball. The combination of speed and leaving a slowing obstacle can be quite powerful.
Command: Shockwave can be used to drag enemies towards you or away from you if you position the Ball properly.
Lay Waste is very strong at farming minions and harassing enemy champions.
Ask your allies to help point out when you should use Requiem to get kills in different lanes.
The Orianna Karthus synergy stats shown here demonstrate the areas of her gameplay that do better (or worse) when paired with Karthus, compared to her overall stats. Significant differences are areas of focus that highlight how her gameplay changes when paired with this other champion.
Overall, Orianna sees a large worsening in her KDA (ratio of kills and assists to deaths) when paired with Karthus. His KDA worsened from NaN to NaN. This worsening shows that Karthus helps Orianna perform not as well in competitive League matches. Yet, the small difference proves that this performance change is only marginal.
When Orianna plays on the same team as Karthus, she gets a small decrease in her total damage output. This change may indicate that Karthus does not support by providing protection for her to deal more damage or that his presence on the team also helps increase the match's duration. Similarly, when Orianna is played together with Karthus on the same side, he usually scores many fewer killing sprees than when she plays alone. This is contrasting evidence that she is worse when playing synergisticly with Karthus.
Additionally, when Orianna plays with Karthus on the same team, she typically takes more damage than when she fights alone. Getting dealt more damage could indicate that Karthus does a poor job of protecting Orianna in teamfights.
There is no one best companion for Orianna that will 100% of the time be her top teammate. However, Karthus is a terrible ally for Orianna. By locking into the same team as Orianna, he decreases their win rate by -9.5% to 38.0%. This signals that there is a terrible bond between Orianna and Karthus that results in them performing not as well together than without each other.
Karthus has a lower difficulty than Orianna. That means you don't need to be careful when arranging Karthus allies to play with, as they will need a lower level of skill to fight well with you.
Working cooperatively, you will likely see an overall large increase in your team’s ability to deal magical damage. Combined, these two can blast through enemies with magic damage.
Although, by aligning Orianna and Karthus together, you may not be giving your other teammates a lot of cover. Plan to include other champions on your team that helps cover this disparity in this pairing's potential.
Regardless of the skill of your Karthus teammate, you should focus on increasing your gold income, warding to avoid ambushes, and taking down objectives. If you heed this simple advice, you should do well, regardless.
If you would like to learn all of the intricacies of Orianna to synergize with Karthus during both the laning and mid / late game phases of LoL rounds, you should keep reading to gather some more tricks and insights into this champion pairing. If you listen to the build and suggestions shown above, you will increase your win rate by a lot.
The most crucial items to focus on in your Orianna and Karthus synergy build include Shadowflame, Stormsurge, and Luden's Companion. When Orianna used at least these three pieces in her build, she performed significantly better when fighting alongside Karthus than with many other commonly used builds. In fact, Orianna boasted an average win rate of 38.0% when playing alongside Karthus with this build.
To have the highest likelihood of vanquishing your oponents, Orianna players should take the Summon Aery, Manaflow Band, Transcendence, Scorch, Biscuit Delivery, and Cosmic Insight runes from the Sorcery and Inspiration rune sets. Out of all the rune combinations that we analyzed for Orianna and Karthus pairings, this set of runes yielded the top win rate. In fact, these runes gave a 38.0% winrate overall.
By default, tips, stats, and builds on how to synergize Karthus with Orianna are displayed for every ranked division. If you want to narrow the stats and builds to a particular rank, you should use the selection menu earlier in the counter matchup guide.