You can set her passive to use hotkeys in the options menu. The default is Shift+F1~F5
Try to use Inherent Glamour sparingly, ineffective uses will put enemies on the alert.
Transfusion instantly deals damage to the enemy before healing Vladimir, making it one of the best last hitting tools in the game.
Cast Hemoplague where it will afflict the most units.
Sanguine Pool pops incoming missiles, so it can be used to dodge disables.
The Neeko Vladimir synergy stats shown here demonstrate the areas of her gameplay that do better (or worse) when paired with Vladimir, compared to her overall stats. Significant differences are areas of focus that highlight how her gameplay changes when paired with this other champion.
Overall, Neeko sees a very large drop in her KDA (ratio of kills and assists to deaths) when paired with Vladimir. His KDA fell from NaN to NaN. This decrease shows that Vladimir helps Neeko perform worse in competitive LoL rounds. Yet, the small difference proves that this performance change is not very impactful.
When Neeko plays on the same team as Vladimir, she observes a little drop in her full damage dealt. This difference could indicate that Vladimir doesn't help cover for her to dish out more damage or that his participation also helps extend the game's duration. Similarly, when Neeko is played together with Vladimir on the same team, he usually scores many fewer killing sprees compared to when she plays without Vladimir. This is contrasting evidence that she is worse when playing with Vladimir.
Additionally, when Neeko plays with Vladimir on the same team, she typically takes a little less damage than when she fights alone. Getting dealt not as much damage may mean that Vladimir does a decent job of protecting Neeko in teamfights.
There is no ideal synergy for Neeko that will always be her #1 ally. Yet, overall, Vladimir is a very typical teammate for Neeko. By playing on the same team as Neeko, he improves their win rate by 0.1% to 49.5%. This clearly indicates that there is only a small bond between Neeko and Vladimir that allows them to perform at the top of their game together than without each other.
Vladimir has a greater difficulty than Neeko. That means Neeko players should be careful when enlisting Vladimir teammates to go into battle on the same side as, as they will have to have a greater level of skill to fight well with you.
Working cooperatively, Neeko players will likely see an overall large increase in your team’s capability to deal magic damage. Combined, these champs can deal quite a lot of AP type damage.
Conversely, by pairing Neeko and Vladimir together, you may not be giving your other allies a lot of AD. We recommend you include other champs on your team that nullifies this gap in their playstyle.
Regardless of your Vladimir ally's ability, you should focus on increasing your income, staying alive by avoiding foolish fights, and clearing objectives. If you do this, you will do well, regardless.
If you would like to learn all of the intricacies of Neeko to pair well with Vladimir during both the early game and mid / late game phases of League games, you should keep reading to pick up a few extra tricks and insights into this champion pairing. If you mind the build and tips shown above, you will grow your win rate by a lot.
The best items to use in your Neeko and Vladimir synergy build include Zaz'Zak's Realmspike, Shadowflame, and Stormsurge. When Neeko combined at least these three pieces in her build, she did a lot better as an ally of Vladimir than with most other common builds. In fact, Neeko had an average winrate of 49.5% when synergizing her build and playstyle to Vladimir with these items in her kit.
To have the best likelihood of defeating your oponents, you should equip the Arcane Comet, Manaflow Band, Transcendence, Scorch, Biscuit Delivery, and Cosmic Insight runes from the Sorcery and Inspiration rune sets. Of all the rune builds players used for Neeko and Vladimir pairings, this set of runes resulted in the highest win rate. Moreover, these runes gave a 49.5% win rate overall.
By default, tips, statistics, and builds on how to synergize Vladimir with Neeko are presented for all skill levels, merged. If you would like to scope the statistics and builds to a particular skill level, you can use the selection menu above.