You can set her passive to use hotkeys in the options menu. The default is Shift+F1~F5
Try to use Inherent Glamour sparingly, ineffective uses will put enemies on the alert.
Contaminate has a large range; apply as many stacks of Deadly Venom as possible before using it.
You can catch up to an enemy out of attack range with Venom Cask.
Twitch's Attack Speed is among the highest in the game; try purchasing items with on-hit effects such as Black Cleaver or Wit's End.
The Neeko Twitch synergy stats shown here demonstrate the areas of her gameplay that do better (or worse) when paired with Twitch, compared to her overall stats. Significant differences are areas of focus that highlight how her gameplay changes when paired with this other champion.
Overall, Neeko sees a large worsening in her KDA (ratio of kills and assists to deaths) when paired with Twitch. His KDA worsened from NaN to NaN. This decrease shows that Twitch helps Neeko perform poorer in ranked League games. Yet, the small difference demonstrates that this performance change is not very impactful.
When Neeko tries to synergize with Twitch, she observes a small decrease in her total damage dealt. This difference could demonstrate that Twitch does not provide protection for her to dish out more damage or that his presence also helps increase the round's duration. Similarly, when Neeko is played alongside Twitch on the same team, he usually scores many fewer killing sprees than when she plays on his own. This is contrasting evidence that she is worse when playing alongside Twitch.
Additionally, when Neeko plays with Twitch on the same team, she often receives a little more damage than when she fights alone. Taking more damage could mean that Twitch does a poor job of protecting Neeko during team fights.
There is no universally accepted best synergy for Neeko that will no matter what be her best ally. Yet, Twitch is a very typical teammate for Neeko. By being on the same team as Neeko, he has no effect on their win rate by 0.0% to 49.4%. This signals that there is a weak strategic relationship between Neeko and Twitch that results in them performing at the same level together than alone.
Twitch has a greater difficulty than Neeko. That means you need to be cautious when enlisting Twitch allies to fight alongside, as they will have to have a greater level of skill to be able to play well with you.
When playing on the same side, you should expect to observe an overall large increase in your team’s ability to deal magic damage. Together, these two can deal quite a lot of AP type damage.
Although, by bringing Neeko and Twitch together, you may not be giving your team a lot of tankyness. We recommend you include other champs on your team that helps cover this relative hole in their playstyle.
Regardless of your Twitch ally's ability, you should focus on maximizing your gold income, warding to avoid ambushes, and clearing objectives. If you do this, you should do well, regardless.
If you would like to truly master Neeko in order to work well with Twitch during both the early game and mid / late game phases of League of Legends games, you should continue reading to gather a few extra lessons on this champion pairing. If you listen to the build and suggestions shown above, you should increase your win rate by a lot.
The most important finished items to use in your Neeko and Twitch synergy build include Rabadon's Deathcap, Hextech Rocketbelt, and Stormsurge. When Neeko bought at least these three great items in her build, she performed significantly better as an ally of Twitch than with most other commonly used builds. In fact, Neeko had an average win rate of 49.4% helping carry Twitch with this build.
To have the greatest chance of defeating your oponents, Neeko players should equip the Arcane Comet, Manaflow Band, Transcendence, Scorch, Cheap Shot, and Ultimate Hunter runes from the Sorcery and Domination rune sets. Out of all the rune builds players picked for Neeko and Twitch pairings, this combination of runes resulted in the highest win rate. Notably, these runes gave a 49.4% winrate overall.
If you want to get Neeko with Twitch collaboration tips and stats for a a specific division, please choose one from the selection menu displayed above. At first, the statistics and guides given are calculated using all rounds with data with these champions.