You can set her passive to use hotkeys in the options menu. The default is Shift+F1~F5
Try to use Inherent Glamour sparingly, ineffective uses will put enemies on the alert.
Melee allies can stack Frost for your Permafrost, keep an eye on who they are attacking.
Save Glacial Prison for encounters where you have teammates present to take advantage of it.
Use Arctic Assault to escape bad situations, interupt channeled spells or chase runners.
The Neeko Sejuani synergy stats shown here demonstrate the areas of her gameplay that do better (or worse) when paired with Sejuani, compared to her overall stats. Significant differences are areas of focus that highlight how her gameplay changes when paired with this other champion.
Overall, Neeko sees a very large drop in her KDA (ratio of kills and assists to deaths) when paired with Sejuani. His KDA fell from NaN to NaN. This worsening shows that Sejuani helps Neeko perform worse in competitive League matches. Yet, the small difference proves that this performance change is only marginal.
When Neeko is an ally to Sejuani, she observes a little increase in her total damage output. This change may indicate that Sejuani helps provide protection for her to dish out more damage or that her participation also helps extend the game's duration. Similarly, when Neeko is played together with Sejuani on the same side, he usually scores many fewer killing sprees than when she plays without Sejuani. This is contrasting evidence that she is worse when playing with Sejuani.
Additionally, when Neeko plays with Sejuani on the same team, she typically receives a little less damage than when she fights alone. Getting dealt not as much damage could mean that Sejuani does a decent job of protecting Neeko in teamfights.
There is no universally accepted best ally for Neeko that will 100% of the time be her top ally. Yet, Sejuani is a very bad ally for Neeko. By locking into the same team as Neeko, she decreases their win rate by -4.4% to 45.0%. This proves that there is an easy to overcome and exploit bond between Neeko and Sejuani that results in them performing not as well together than without each other.
Sejuani has a lower difficulty than Neeko. That means you don't need to be very careful when lining up Sejuani allies to go into battle on the same side as, as they will require a relatively low level of skill to work well with you.
Fighting alongside, you should expect to see an overall large increase in your team’s capability to deal magical damage. When paired, these champs are able to dish out a surprising amount of magic type damage.
Conversely, by grouping Neeko and Sejuani together, you probably will not be providing your other allies a lot of AD. We recommend you bring other champions on your team that nullifies this relative disparity in their capabilities.
Regardless of the ability of your Sejuani ally, you should focus on increasing your gold income, staying alive by avoiding foolish fights, and taking down objectives. If you heed this simple advice, you should do well anyway.
To learn all of the intricacies of Neeko to synergize with Sejuani during both the lane and mid / late game phases of League of Legends games, you should keep reading to gather some more lessons on this champion pairing. If you listen to the build and tips presented above, you should increase your win rate significantly.
The ideal finished items to include in your Neeko and Sejuani synergy build include Hextech Rocketbelt, Zhonya's Hourglass, and Stormsurge. When Neeko combined at least these three pieces in her build, she did a lot better when fighting alongside Sejuani than with many other typical builds. In fact, Neeko boasted an average winrate of 45.0% helping carry Sejuani with these items in her kit.
To have the best likelihood of beating your oponents, you should use the Arcane Comet, Manaflow Band, Transcendence, Scorch, Biscuit Delivery, and Cosmic Insight runes from the Sorcery and Inspiration rune sets. Out of all the rune combinations players used for this team composition, this mixture of runes resulted in the highest win rate. In fact, these runes gave a 45.0% winrate overall.
By default, tips, statistics, and builds on how to synergize Sejuani with Neeko are presented for all skill levels, merged. If you would like to narrow the stats and builds to a particular player tier, you can use the selection menu earlier on the page.