You can set her passive to use hotkeys in the options menu. The default is Shift+F1~F5
Try to use Inherent Glamour sparingly, ineffective uses will put enemies on the alert.
Spell Flux's short cooldown allows it to be used to spread Flux to many enemies.
Use Overload's passive to optimize for maximum damage or maximum speed.
Ryze can move and cast other spells while Realm Warp is charging without cancelling the portal.
The Neeko Ryze synergy stats shown here demonstrate the areas of her gameplay that do better (or worse) when paired with Ryze, compared to her overall stats. Significant differences are areas of focus that highlight how her gameplay changes when paired with this other champion.
Overall, Neeko sees a very large drop in her KDA (ratio of kills and assists to deaths) when paired with Ryze. His KDA worsened from NaN to NaN. This negative change shows that Ryze helps Neeko perform poorer in ranked LoL rounds. Yet, the small difference shows that this performance change is only marginal.
When Neeko is an ally to Ryze, she gets a little drop in her complete damage dealt. This difference could indicate that Ryze doesn't help cover for her to dish out more damage or that his presence also helps increase the round's duration. Similarly, when Neeko is played together with Ryze on the same team, he usually scores many fewer killing sprees compared to when she plays on his own. This is contrasting evidence that she is worse when playing alongside Ryze.
Additionally, when Neeko plays with Ryze on the same team, she often receives a little more damage than when she plays alone. Getting dealt more damage may mean that Ryze does a poor job of covering Neeko during teamfights.
There is no top companion for Neeko that will 100% of the time be her ideal synergy. However, overall, Ryze is a very bad teammate for Neeko. By being on the same team as Neeko, he lowers their win rate by -3.8% to 45.6%. This clearly indicates that there is a very bad bond between Neeko and Ryze that allows them to perform not as well together than without each other.
Ryze has a greater difficulty than Neeko. That means you need to be cautious when finding Ryze allies to go into battle on the same side as, as they will have to have a greater level of skill to fight well with you.
Fighting alongside, Neeko players should witness an overall large increase in your team’s ability to to do a lot of AP damage. When paired, these champs can blast through enemies with magic damage.
Conversely, by bringing Neeko and Ryze together, you may not be giving your side enough AD. Plan to pick other champions on your team that helps cover this relative gap in this pairing's kit.
Regardless of your Ryze ally's ability, you need to focus on maximizing your income, outlasting your enemies, and taking down objectives. If you follow these simple suggestions, you should do well, regardless.
If you would like to learn all of the intricacies of Neeko in order to synergize with Ryze during both the laning and mid / late game phases of League rounds, you should keep reading to pick up a few extra tricks and insights into this champion pairing. If you listen to the build and suggestions presented above, you will grow your win rate by a lot.
The top items to focus on in your Neeko and Ryze synergy build consist of Hextech Rocketbelt, Zaz'Zak's Realmspike, and Stormsurge. When Neeko included at least these three pieces in her build, she did a lot better as an ally of Ryze than with many other commonly used builds. In fact, Neeko had an average winrate of 45.6% when playing alongside Ryze with these items in her kit.
To have the best probability of vanquishing your oponents, you should equip the Arcane Comet, Manaflow Band, Transcendence, Scorch, Biscuit Delivery, and Cosmic Insight runes from the Sorcery and Inspiration rune sets. Of all the rune builds that we analyzed for this team composition, this composite of runes resulted in the top win rate. In fact, these runes averaged a 45.6% winrate overall.
By default, tips, statistics, and builds on how to team up Ryze with Neeko are shown for every ranked division. If you want to narrow the stats and builds to a specific division, you may use the selection menu earlier on the page.