You can set her passive to use hotkeys in the options menu. The default is Shift+F1~F5
Try to use Inherent Glamour sparingly, ineffective uses will put enemies on the alert.
While ganking, consider aiming Dredge Line at nearby terrain and following it up with Riptide for a higher hit rate.
Riptide has a delayed blast timing on activation - you can use this while running away or when enemies are incoming to serve as a deterrent.
The Neeko Nautilus synergy stats shown here demonstrate the areas of her gameplay that do better (or worse) when paired with Nautilus, compared to her overall stats. Significant differences are areas of focus that highlight how her gameplay changes when paired with this other champion.
Overall, Neeko sees a large worsening in her KDA (ratio of kills and assists to deaths) when paired with Nautilus. His KDA fell from NaN to NaN. This fall shows that Nautilus helps Neeko perform not as well in competitive League of Legends matches. Yet, the small difference proves that this performance change is not very impactful.
When Neeko plays on the same team as Nautilus, she observes a small increase in her total damage dealt. This difference could signal that Nautilus helps provide protection for her to deal more damage or that his participation also helps extend the game's duration. Similarly, when Neeko is played with Nautilus on the same side, he usually scores many fewer killing sprees than when she plays alone. This is contrasting evidence that she is worse when playing alongside Nautilus.
Additionally, when Neeko plays with Nautilus on the same team, she typically receives a little less damage than when she fights alone. Getting dealt not as much damage could indicate that Nautilus does a decent job of protecting Neeko during team fights.
There is no top ally for Neeko that will 100% of the time be her #1 synergy. However, Nautilus is a very typical ally for Neeko. By locking into the same side as Neeko, he lowers their win rate by -0.9% to 48.5%. This signals that there is only a small synergy between Neeko and Nautilus that allows them to perform not as well together than without each other.
Nautilus has a greater difficulty than Neeko. That means you should be careful when arranging Nautilus comrades to go into battle on the same side as, as they will require a greater level of skill to be able to do well with you.
Working cooperatively, you will likely see an overall large increase in your team’s capacity to to do a lot of AP damage. When paired, these two are able to dish out a surprising amount of magic type damage.
In contrast, by aligning Neeko and Nautilus together, you may not be providing your other teammates a great deal of anti-tank damage dealing potential. Make sure to pick other champs on your team that offsets this hole in their abilities.
Regardless of the ability of your Nautilus teammate, you need to focus on maximizing your income, staying alive by avoiding foolish fights, and taking down objectives. If you follow these simple suggestions, you should do well, regardless.
If you would like to learn all of the intricacies of Neeko to work well with Nautilus during both the lane and mid / late game phases of League of Legends, you should continue reading to learn a few extra tips and tricks for this champion pairing. If you listen to the build and stats displayed here, you will increase your win rate by a lot.
The top finished items to include in your Neeko and Nautilus synergy build include Zhonya's Hourglass, Shadowflame, and Stormsurge. When Neeko bought at least these three items in her build, she performed much better when paired up with Nautilus than with most other typical item sets. In fact, Neeko boasted an average win rate of 48.5% helping carry Nautilus with these items in her kit.
To have the best probability of annihilating your oponents, you should take the Arcane Comet, Manaflow Band, Transcendence, Scorch, Biscuit Delivery, and Cosmic Insight runes from the Sorcery and Inspiration rune sets. Of all the rune combinations players picked for this team composition, this set of runes resulted in the best win rate. Moreover, these runes provided a 48.5% winrate overall.
By default, tips, stats, and builds on how to synergize Nautilus with Neeko are given for all ranked divisions combined. To scope the statistics and builds to a particular rank, you can use the selection menu located earlier on the page.