You can set her passive to use hotkeys in the options menu. The default is Shift+F1~F5
Try to use Inherent Glamour sparingly, ineffective uses will put enemies on the alert.
Use Call of the Void and Nether Grasp to renew the duration of Malefic Visions on enemies.
Wait to cast Void Swarm until there are nearby enemies for the Voidling to attack or kill.
Avoiding damage in lane maximizes the uptime on Void Shift, increasing Malzahar's safety dramatically.
The Neeko Malzahar synergy stats shown here demonstrate the areas of her gameplay that do better (or worse) when paired with Malzahar, compared to her overall stats. Significant differences are areas of focus that highlight how her gameplay changes when paired with this other champion.
Overall, Neeko sees a very large drop in her KDA (ratio of kills and assists to deaths) when paired with Malzahar. His KDA decreased from NaN to NaN. This fall shows that Malzahar helps Neeko perform not as well in competitive LoL games. Yet, the small difference indicates that this performance change is not very impactful.
When Neeko is an ally to Malzahar, she observes a small decrease in her full damage dealt. This change may signal that Malzahar does not help cover for her to dish out more damage or that his allyship also helps extend the match's duration. Similarly, when Neeko is played with Malzahar on the same side, he usually scores many fewer killing sprees compared to when she plays on his own. This is contrasting evidence that she is worse when playing alongside Malzahar.
Moreover, when Neeko plays with Malzahar on the same team, she on average takes a little more damage than when she fights alone. Receiving more damage may indicate that Malzahar does a poor job of protecting Neeko during team fights.
There is no perfect ally for Neeko that will always be her best synergy. Yet, Malzahar is a decent ally for Neeko. By being on the same team as Neeko, he improves their win rate by 1.6% to 51.0%. This proves that there is pretty good strategic relationship between Neeko and Malzahar that allows them to perform at the top of their game together than alone.
Malzahar has a greater difficulty than Neeko. That means you need to be careful when arranging Malzahar teammates to play with, as they will have to have a greater level of skill to do well with you.
Playing on the same side, you should see an overall large increase in your team’s capacity to deal magical damage. Combined, these champs can deal quite a lot of AP type damage.
In contrast, by aligning Neeko and Malzahar together, you may not be providing your team much attack damage. Plan to bring other champions on your team that neutralizes this relative hole in this pairing's playstyle.
Regardless of the ability of your Malzahar ally, you need to focus on maximizing your income, warding to avoid ambushes, and taking down objectives. If you heed this simple advice, you should do well anyway.
If you would like to truly master Neeko to synergize with Malzahar during both the early game and mid / late game phases of League rounds, you should keep reading to master additional lessons on this champion pairing. If you listen to the build and tips shown here, you should increase your win rate significantly.
The ideal finished items to include in your Neeko and Malzahar synergy build include Zhonya's Hourglass, Zaz'Zak's Realmspike, and Stormsurge. When Neeko used at least these three items in her build, she performed a lot better as an ally of Malzahar than with many other common item sets. In fact, Neeko boasted an average winrate of 51.0% when synergizing her build and playstyle to Malzahar with these items in her kit.
To have the best likelihood of vanquishing your oponents, Neeko players should take the Arcane Comet, Manaflow Band, Transcendence, Scorch, Biscuit Delivery, and Cosmic Insight runes from the Sorcery and Inspiration rune sets. Out of all the rune sets players picked for Neeko and Malzahar pairings, this order of runes yielded the best win rate. In fact, these runes averaged a 51.0% winrate overall.
By default, tips, statistics, and builds on how to pair Malzahar with Neeko are shown for all ranked divisions. If you want to filter the statistics and builds to a specific skill level, you can use the selection menu located earlier in the counter matchup guide.